Short-term anatomic effect of ranibizumab for polypoidal choroidal vasculopathy

被引：33
作者：
Reche-Frutos, J. [1 ]
Calvo-Gonzalez, C. [1 ]
Donate-Lopez, J. [1 ]
Garcia-Feijoo, J. [1 ]
Leila, M. [1 ]
Garcia-Sanchez, J. [1 ]
机构：
[1] Hosp Clin Univ San Carlos, Dept Ophthalmol, Madrid 28040, Spain
来源：
EUROPEAN JOURNAL OF OPHTHALMOLOGY | 2008年 / 18卷 / 04期
关键词：
Polypoidal choroidal vasculopathy; Ranibizumab; Optical coherence tomography; Indocyanine green angiography;
D O I：
10.1177/112067210801800427
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
PURPOSE. To assess the short-term anatomic effect of intravitreal ranibizumab for polypoidal choroidal vasculopathy. METHODS. All patients had undergone a full ophthalmic examination. A monthly injection of ranibizumab was performed for 3 months. Indocyanine angiography (ICG) and optical coherence tomography (OCT) were performed 1 month after the third-month ranibizumab injection. RESULTS. Polyps disappeared on ICG angiography in 9 out of 13 lesions (69.2%). Retinal thickness diminished significantly on OCT (p=0.02). In our series we noticed a significant reduction of the percentage of patients presenting with subretinal fluid (p=0.02) and pigment epithelium detachment between the initial and final visits (0.016). In addition, we noticed that BCVA increased significantly (p=0.02). CONCLUSIONS. Monthly intravitreal injection of ranibizumab for 3 months has a short-term beneficial anatomic effect. (Eur J Ophthalmol 2008; 18: 645-8)
引用
收藏
页码：645 / 648
页数：4
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