Microfluidic multiplexed partitioning enables flexible and effective utilization of magnetic sensor arrays

被引：11

作者：

Bechstein, Daniel J. B. ^{[1
]}

Ng, Elaine ^{[2
]}

Lee, Jung-Rok ^{[1
]}

Cone, Stephanie G. ^{[3
]}

Gaster, Richard S. ^{[2
,4
]}

Osterfeld, Sebastian J. ^{[5
]}

Hall, Drew A. ^{[6
,7
]}

Weaver, James A. ^{[6
]}

Wilson, Robert J. ^{[8
]}

Wang, Shan X. ^{[6
,8
]}

机构：

[1] Stanford Univ, Mech Engn, Stanford, CA 94305 USA

[2] Stanford Univ, Bioengn, Stanford, CA 94305 USA

[3] Univ N Carolina, Biomed Engn, Chapel Hill, NC 27514 USA

[4] Harvard Univ, Med, Cambridge, MA 02138 USA

[5] MagArray Inc, Milpitas, CA 95035 USA

[6] Stanford Univ, Elect Engn, Stanford, CA 94305 USA

[7] Univ Calif San Diego, Elect & Comp Engn, La Jolla, CA 92093 USA

[8] Stanford Univ, Mat Sci, Stanford, CA 94305 USA

来源：

LAB ON A CHIP | 2015年 / 15卷 / 22期

基金：

美国国家科学基金会;

关键词：

PROTEIN; FABRICATION; MICROARRAYS; BIOSENSORS; FUTURE; MARKER; TROP2;

D O I：

10.1039/c5lc00953g

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrate microfluidic partitioning of a giant magnetoresistive sensor array into individually addressable compartments that enhances its effective use. Using different samples and reagents in each compartment enables measuring of cross-reactive species and wide dynamic ranges on a single chip. This compartmentalization technique motivates the employment of high density sensor arrays for highly parallelized measurements in lab-on-a-chip devices.

引用

页码：4273 / 4276

页数：4

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