Titanium Salalen Catalysts Based on cis-1,2-Diaminocyclohexane: Enantioselective Epoxidation of Terminal Non-Conjugated Olefins with H2O2

被引：63

作者：

Berkessel, Albrecht ^{[1
]}

Guenther, Thomas ^{[1
]}

Wang, Qifang ^{[1
]}

Neudoerfl, Joerg-M. ^{[1
]}

机构：

[1] Univ Cologne, Dept Chem, D-50939 Cologne, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 32期

关键词：

asymmetric catalysis; cis-DACH; epoxidation; hydrogen peroxide; titanium; AQUEOUS HYDROGEN-PEROXIDE; ASYMMETRIC EPOXIDATION; LIGANDS; COMPLEX;

D O I：

10.1002/anie.201210198

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Terminal, non-conjugated olefins, such as 1-octene, are difficult to epoxidize asymmetrically. Ti salalen complexes based on cis-1,2- diaminocyclohexane catalyze this demanding reaction giving high yields and enantioselectivities (up to 95 % ee), with H2O2 as the oxidant. The X-ray structures of the μ-oxo and peroxo complexes shed light on the coordination behavior of this novel class of ligands.

引用

页码：8467 / 8471

页数：5

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