BIOCHEMISTRY Oxidation controls the DUB step

被引:13
作者
Clague, Michael J. [1 ]
机构
[1] Univ Liverpool, Dept Cellular & Mol Physiol, Liverpool L69 3BX, Merseyside, England
关键词
DEUBIQUITINASES;
D O I
10.1038/497049a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Reversible oxidation of amino-acid residues can directly regulate the activity of cellular enzymes. This principle has now been extended to deubiquitinating enzymes, with implications for cell signalling and protein turnover.
引用
收藏
页码:49 / 50
页数:3
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