TGF-β synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression

被引：0
|
作者：
Fujii, Makiko [1 ]
Toyoda, Takeshi [1 ]
Nakanishi, Hayao [1 ]
Yatabe, Yasushi [2 ]
Sato, Ayuko [3 ]
Matsudaira, Yasue [1 ]
Ito, Hidemi [1 ]
Murakami, Hideki [1 ]
Kondo, Yutaka [1 ]
Kondo, Eisaku [1 ]
Tsujimura, Tohru [3 ]
Hida, Toyoaki [2 ]
Osada, Hirotaka [1 ]
Sekido, Yoshitaka [1 ]
机构：
[1] Aichi Canc Ctr, Res Inst, Nagoya, Aichi 464, Japan
[2] Aichi Canc Ctr Hosp, Nagoya, Aichi 464, Japan
[3] Hyogo Coll Med, Nishinomiya, Hyogo 6638501, Japan
来源：
CANCER RESEARCH | 2012年 / 72卷
关键词：
D O I：
10.1158/1538-7445.AM2012-3082
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3082
引用
收藏
页数：2
相关论文
共 44 条
  • [1] TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth
    Fujii, Makiko
    Toyoda, Takeshi
    Nakanishi, Hayao
    Yatabe, Yasushi
    Sato, Ayuko
    Matsudaira, Yasue
    Ito, Hidemi
    Murakami, Hideki
    Kondo, Yutaka
    Kondo, Eisaku
    Hida, Toyoaki
    Tsujimura, Tohru
    Osada, Hirotaka
    Sekido, Yoshitaka
    JOURNAL OF EXPERIMENTAL MEDICINE, 2012, 209 (03): : 479 - 494
  • [2] Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma TGFβ signaling and defects in the Hippo signaling cascade
    Fujii, Makiko
    Nakanishi, Hayao
    Toyoda, Takeshi
    Tanaka, Ichidai
    Kondo, Yutaka
    Osada, Hirotaka
    Sekido, Yoshitaka
    CELL CYCLE, 2012, 11 (18) : 3373 - 3379
  • [3] TGF-β1 induces fibronectin expression in renal fibroblasts through connective tissue growth factor (CTGF)-JNK dependent pathway.
    Yokoi, H
    Mukoyama, M
    Sugawara, A
    Mori, K
    Suganami, T
    Yahata, K
    Makino, H
    Nagae, T
    Fujinaga, Y
    Sawai, K
    Yoshimoto, A
    Yoshioka, T
    Koshikawa, M
    Nakao, K
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 : 315A - 315A
  • [4] Modulation of transforming growth factor-β (TGF-β) pathway restricted Smad activation and expression in lung fibroblasts by TGF-β
    Zhao, Y
    FASEB JOURNAL, 2001, 15 (04): : A160 - A160
  • [5] Angiotensin II increases CTGF expression via MAPKs/TGF-β1/TRAF6 pathway in atrial fibroblasts
    Gu, Jun
    Liu, Xu
    Wang, Quan-xing
    Tan, Hong-wei
    Guo, Meng
    Jiang, Wei-feng
    Zhou, Li
    EXPERIMENTAL CELL RESEARCH, 2012, 318 (16) : 2105 - 2115
  • [6] Inhibition of TGF-β-stimulated CTGF gene expression and anchorage-independent growth by cAMP identifies a CTGF-dependent restriction point in the cell cycle
    Kothapalli, D
    Hayashi, N
    Grotendorst, GR
    FASEB JOURNAL, 1998, 12 (12): : 1151 - 1161
  • [7] Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19
    Zhu, Jing
    Duy Nguyen
    Ouyang, Hong
    Zhang, Xiao-Hui
    Chen, Xiao-Ming
    Zhang, Kang
    INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 2013, 6 (01) : 8 - 14
  • [8] Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19
    Jing Zhu
    Duy Nguyen
    Hong Ouyang
    Xiao-Hui Zhang
    Xiao-Ming Chen
    Kang Zhang
    International Journal of Ophthalmology, 2013, 6 (01) : 8 - 14
  • [9] Connective tissue growth factor (CTGF) expression in rat corneas after photorefractve keratectomy and stimulation by transforming growth factor beta (TGF-β).
    Blalock, TD
    Varela, JC
    Goldstein, MH
    Grotendorst, GR
    Schultz, GS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2001, 42 (04) : S902 - S902
  • [10] CTGF Inhibits the Differentiation of Chicken Preadipocytes via the TGFβ/Smad3 Signaling Pathway or by Inducing the Expression of ACTG2
    Zhou, Jiamei
    Wang, Shuping
    Shen, Linyong
    Song, Yan
    Cao, Zhiping
    Li, Yumao
    Luan, Peng
    Li, Hui
    Bai, Xue
    Zhang, Hui
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 72 (35) : 19413 - 19423
12345