Bioactive N-isobutylamides from the flower buds of Spilanthes acmella

被引：125

作者：

Ramsewak, RS

Erickson, AJ

Nair, MG ^{[1
]}

机构：

[1] Michigan State Univ, Dept Hort, E Lansing, MI 48824 USA

[2] Michigan State Univ, Natl Food Safety & Toxicol Ctr, E Lansing, MI 48824 USA

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 06期

关键词：

Spilanthes acmella; Compositae; Heliantheae; N-isobutyl amides; acetylenic compounds; spilanthol;

D O I：

10.1016/S0031-9422(99)00101-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The hexane extract of dried flower buds of Spilanthes acmella afforded three N-isobutyl amides: spilanthol, undeca-2E,7Z,9E-trienoic acid isobutylamide and undeca-2E-en-8,10-diynoic acid isobutylamide. Their structures were determined by H-1 and C-13 NMR, MS and GC-MS spectroscopic methods. All were active against Aedes aegyptii larvae and Helicoverpa tea neonates at 12.5 and 250 mu g/mL concentrations, respectively. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：729 / 732

页数：4

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