Relearning the Lessons of Genomic Stability of Human Cells During Expansion in Culture: Implications for Clinical Research

被引:33
作者
Prockop, Darwin J. [1 ]
Keating, Armand [2 ]
机构
[1] Texas A&M Hlth Sci, Coll Med, Inst Regenerat Med Scott & White, Dept Med, Temple, TX USA
[2] Princess Margaret Hosp, Cell Therapy Program, Toronto, ON, Canada
关键词
D O I
10.1002/stem.1103
中图分类号
Q813 [细胞工程];
学科分类号
摘要
引用
收藏
页码:1051 / 1052
页数:2
相关论文
共 10 条
[1]   Large-Scale Analysis Reveals Acquisition of Lineage-Specific Chromosomal Aberrations in Human Adult Stem Cells [J].
Ben-David, Uri ;
Mayshar, Yoav ;
Benvenisty, Nissim .
CELL STEM CELL, 2011, 9 (02) :97-102
[2]  
Casiraghi F, 2012, STEM CELL REV
[3]   Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing [J].
Dass, Crispin R. ;
Ek, Eugene T. H. ;
Choong, Peter F. M. .
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2007, 133 (03) :193-198
[4]   HUMAN DIPLOID CELL STRAINS [J].
HAYFLICK, L ;
PERKINS, F ;
STEVENSON, RE .
SCIENCE, 1964, 143 (360) :976-&
[5]  
Petricciani JC, 1998, DEV BIOLOGICALS, V93, P5
[6]   Defining the risks of mesenchymal stromal cell therapy [J].
Prockop, Darwin J. ;
Brenner, Malcolm ;
Fibbe, Willem E. ;
Horwitz, Edwin ;
Le Blanc, Katarina ;
Phinney, Donald G. ;
Simmons, Paul J. ;
Sensebe, Lug ;
Keating, Armand .
CYTOTHERAPY, 2010, 12 (05) :576-578
[7]   Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes [J].
Romanov, SR ;
Kozakiewicz, BK ;
Holst, CR ;
Stampfer, MR ;
Haupt, LM ;
Tlsty, TD .
NATURE, 2001, 409 (6820) :633-637
[8]  
Rosolowsky M, 1998, DEV BIOL STAND, V93, P109
[9]  
Strassberg M, 2011, EXPERT REV MOL DIAGN, V11, P579, DOI [10.1586/ERM.11.43, 10.1586/erm.11.43]
[10]  
1979, J BIOL STAND, V7, P397