Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults

被引:5
|
作者
Yildiz, Gizem Y. [1 ]
Vilsten, Julian S. [1 ]
Millard, Amy Siobhan [1 ]
Chouinard, Philippe A. [1 ]
机构
[1] La Trobe Univ, Sch Psychol & Publ Hlth, Dept Psychol & Counselling, Melbourne, Vic, Australia
关键词
Autism-spectrum quotient (AQ); Magnetic resonance imaging (MRI); Primary visual area (V1); Grey-matter thickness; Retinotopy; SPECTRUM QUOTIENT AQ; FUNCTIONING AUTISM; CHILDREN; SEARCH; PARENTS; ORGANIZATION; INDIVIDUALS; PERCEPTION; ACTIVATION; DISORDERS;
D O I
10.1007/s10803-020-04553-w
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
We examined whether functional and structural variability in the primary visual area (V1) correlated with autism traits. Twenty-nine participants (16 males;M-Age = 26.4 years,SDAge = 4.0 years) completed the autism-spectrum quotient (AQ) questionnaire prior to a magnetic resonance imaging session. The total AQ scores was used to assess the degree of self-reported autism traits. The average functional activation in V1 to visual stimulation and its average grey-matter thickness were calculated. There were no correlations between functional activation in V1 and autism traits. Conversely, grey-matter thickness of the left but not the right V1 correlated with autism traits. We conclude that structural changes in the left V1 could be a marker for the presence of autism traits.
引用
收藏
页码:405 / 417
页数:13
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  • [1] Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults
    Gizem Y. Yildiz
    Julian S. Vilsten
    Amy Siobhan Millard
    Philippe A. Chouinard
    Journal of Autism and Developmental Disorders, 2021, 51 : 405 - 417