Multifunctional self-fluorescent polymer nanogels for label-free imaging and drug delivery

被引：55

作者：

Chen, Ying ^{[1
,2
]}

Wilbon, Perry A. ^{[1
]}

Zhou, Juhua ^{[3
]}

Nagarkatti, Mitzi ^{[3
]}

Wang, Chunpeng ^{[2
]}

Chu, Fuxiang ^{[2
]}

Tang, Chuanbing ^{[1
]}

机构：

[1] Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA

[2] Chinese Acad Forestry, Inst Chem Ind Forestry Prod, Nanjing 210042, Jiangsu, Peoples R China

[3] Univ S Carolina, Sch Med, Dept Pathol Microbiol & Immunol, Columbia, SC 29209 USA

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 03期

基金：

美国国家科学基金会;

关键词：

ROSIN; BIOMOLECULES;

D O I：

10.1039/c2cc37386f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multifunctional abietane-based polymer nanogels were fabricated for label-free cell imaging and drug delivery. The self-fluorescent abietane as the framework of carriers enables the imaging without the need for external fluorescent probes, while abietane-based nanogels exhibit low in vitro cytotoxicity.

引用

页码：297 / 299

页数：3

共 36 条

[1] PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect [J].

Acharya, Sarbari ;

Sahoo, Sanjeeb K. .

ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (03) :170-183

[2] Synthesis of Hydroxypropylcellulose-poly(acrylic acid) Particles with Semi-interpenetrating Polymer Network Structure [J].

Chen, Ying ;

Ding, Dan ;

Mao, Zhiqing ;

He, Yafeng ;

Hu, Yong ;

Wu, Wei ;

Jiang, Xiqun .

BIOMACROMOLECULES, 2008, 9 (10) :2609-2614

[3] Amphipathic antibacterial agents using cationic methacrylic polymers with natural rosin as pendant group [J].

Chen, Ying ;

Wilbon, Perry A. ;

Chen, Yung Pin ;

Zhou, Juhua ;

Nagarkatti, Mitzi ;

Wang, Chunpeng ;

Chu, Fuxiang ;

Decho, Alan W. ;

Tang, Chuanbing .

RSC ADVANCES, 2012, 2 (27) :10275-10282

[4] Hollow Core-Porous Shell Structure Poly(acrylic acid) Nanogels with a Superhigh Capacity of Drug Loading [J].

Chen, Ying ;

Zheng, Xianchuang ;

Qian, Hanqing ;

Mao, Zhiqing ;

Ding, Dan ;

Jiang, Xiqun .

ACS APPLIED MATERIALS & INTERFACES, 2010, 2 (12) :3532-3538

[5] Nanospheres-Incorporated Implantable Hydrogel as a Trans-Tissue Drug Delivery System [J].

Ding, Dan ;

Zhu, Zhenshu ;

Li, Rutian ;

Li, Xiaolin ;

Wu, Wei ;

Jiang, Xiqun ;

Liu, Baorui .

ACS NANO, 2011, 5 (04) :2520-2534

[6] Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy [J].

Freudiger, Christian W. ;

Min, Wei ;

Saar, Brian G. ;

Lu, Sijia ;

Holtom, Gary R. ;

He, Chengwei ;

Tsai, Jason C. ;

Kang, Jing X. ;

Xie, X. Sunney .

SCIENCE, 2008, 322 (5909) :1857-1861

[7] In vivo molecular and cellular imaging with quantum dots [J].

Gao, XH ;

Yang, LL ;

Petros, JA ;

Marshal, FF ;

Simons, JW ;

Nie, SM .

CURRENT OPINION IN BIOTECHNOLOGY, 2005, 16 (01) :63-72

[8] Sub-micron poly(N-isopropylacrylamide) particles as temperature responsive vehicles for the detachment and delivery of human cells [J].

Hopkins, Sally ;

Carter, Steven R. ;

Haycock, John W. ;

Fullwood, Nigel J. ;

MacNeil, Sheila ;

Rimmer, Stephen .

SOFT MATTER, 2009, 5 (24) :4928-4937

[9] Noble Metals on the Nanoscale: Optical and Photothermal Properties and Some Applications in Imaging, Sensing, Biology, and Medicine [J].

Jain, Prashant K. ;

Huang, Xiaohua ;

El-Sayed, Ivan H. ;

El-Sayed, Mostafa A. .

ACCOUNTS OF CHEMICAL RESEARCH, 2008, 41 (12) :1578-1586

[10] Cellulose: Fascinating biopolymer and sustainable raw material [J].

Klemm, D ;

Heublein, B ;

Fink, HP ;

Bohn, A .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (22) :3358-3393

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