Cervical CUP syndrome

被引：7

作者：

Mozet, C. ^{[1
]}

Wichmann, G. ^{[1
]}

Stumpp, P. ^{[2
]}

Dietzsch, S. ^{[3
]}

Dietz, A. ^{[1
]}

机构：

[1] Univ Leipzig, Klin & Poliklin Hals Nasen & Ohrenheilkunde, D-04103 Leipzig, Germany

[2] Univ Leipzig, Klin & Poliklin Diagnost & Intervent Radiol, D-04103 Leipzig, Germany

[3] Univ Leipzig, Klin Strahlentherapie, D-04103 Leipzig, Germany

来源：

ONKOLOGE | 2013年 / 19卷 / 01期

关键词：

Cancer of unknown primary; Head and neck tumors; Metastasis; Adenocarcinomas; Squamous cell carcinomas; SQUAMOUS-CELL-CARCINOMA; LYMPH-NODE METASTASES; POSITRON-EMISSION-TOMOGRAPHY; UNKNOWN PRIMARY TUMORS; LOCALLY ADVANCED HEAD; NECK-CANCER; CHEMOTHERAPY; MANAGEMENT; RADIOTHERAPY; MODALITY;

D O I：

10.1007/s00761-012-2315-x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Whenever the first diagnosis of a solid malignancy is found in lymphoid tissue and detection of the primary tumor during the initial diagnostic procedures is not successful, this syndrome is called CUP (cancer of unknown primary). When extensive diagnostic steps finally lead to detection of the primary, then an initial cup syndrome can be assumed in contrast to true CUP syndromes, where the primary tumor remains unrevealed. Most CUP metastases are adenocarcinomas, followed by poorly differentiated carcinomas, squamous cell carcinomas, and neuroendocrine tumors. Metastasis of unknown primaries occurring in lymph nodes of the neck region have a poor prognosis and is predominantly associated with worse prognosis than most other head and neck tumors, which however does depend on various factors. In this article, we introduce diagnostic steps with modern techniques like PET-CT/MRI, and review therapeutic options and prognosis in patients with cervical CUP syndrome.

引用

页码：44 / 51

页数：8