Development of a small-molecule inhibitor targeting the Wnt signaling pathway.

被引:0
|
作者
Yamada, Tesshi [1 ]
Masuda, Mari [1 ]
Sawa, Masaaki [2 ]
机构
[1] Natl Canc Ctr, Res Inst, Tokyo 104, Japan
[2] Carna Biosci Inc, Kobe, Hyogo, Japan
关键词
D O I
10.1158/1535-7163.TARG-13-A132
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A132
引用
收藏
页数:1
相关论文
共 50 条
  • [1] A small-molecule agonist of the wnt signaling pathway
    Liu, J
    Wu, X
    Mitchell, B
    Kintner, C
    Ding, S
    Schultz, PG
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (13) : 1987 - 1990
  • [2] Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer
    Liu, Zhiqing
    Wang, Pingyuan
    Wold, Eric A.
    Song, Qiaoling
    Zhao, Chenyang
    Wang, Changyun
    Zhou, Jia
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (08) : 4257 - 4288
  • [3] Small-molecule synergist of the Wnt/β-catenin signaling pathway
    Zhang, Qisheng
    Major, Michael B.
    Takanashi, Shinichi
    Camp, Nathan D.
    Nishiya, Naoyuki
    Peters, Eric C.
    Ginsberg, Mark H.
    Schultz, Peter G.
    Moon, Randall T.
    Ding, Sheng
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (18) : 7444 - 7448
  • [4] Identification and Characterization of a Small-Molecule Inhibitor of Wnt Signaling in Glioblastoma Cells
    De Robertis, Alessandra
    Valensin, Silvia
    Rossi, Marco
    Tunici, Patrizia
    Verani, Margherita
    De Rosa, Antonella
    Giordano, Cinzia
    Varrone, Maurizio
    Nencini, Arianna
    Pratelli, Carmela
    Benicchi, Tiziana
    Bakker, Annette
    Hill, Jeffrey
    Sangthongpitag, Kanda
    Pendharkar, Vishal
    Liu, Boping
    Ng, Fui Mee
    Then, Siew Wen
    Tai, Shi Jing
    Cheong, Seong-Moon
    He, Xi
    Caricasole, Andrea
    Salerno, Massimiliano
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (07) : 1180 - 1189
  • [5] Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics
    Zheng, Shilong
    Liu, Jiawang
    Wu, Yanyuan
    Huang, Tien L.
    Wang, Guangdi
    FUTURE MEDICINAL CHEMISTRY, 2015, 7 (18) : 2485 - 2505
  • [6] Discovery of Small-Molecule Inhibitors of the PTK7/?-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer
    Ganier, Laetitia
    Betzi, Stephane
    Derviaux, Carine
    Roche, Philippe
    Dessaux, Charlotte
    Muller, Christophe
    Hoffer, Laurent
    Morelli, Xavier
    Borg, Jean-Paul
    ACS CHEMICAL BIOLOGY, 2022, 17 (05) : 1061 - 1072
  • [7] Identification of molecular target for small-molecule tumor inhibitor targeting Myc pathway
    Claassen, Gisela
    Vaillancourt, Mei
    Sirisoma, Nilantha
    Zhang, Han Zhong
    Kemnitzer, William
    May, Chris
    Cai, Sul Xiong
    Tseng, Ben
    Drewe, John
    CANCER RESEARCH, 2009, 69
  • [8] Small-molecule inhibitor LF3 restrains the development of pulmonary hypertension through the Wnt/β-catenin pathway
    Lei, Yong
    Yang, Qi
    Nie, Yongmei
    Wan, Juyi
    Deng, Mingbin
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 53 (10) : 1277 - 1289
  • [9] Small-molecule modulators of Hh and Wnt signaling pathways
    Kiselyov, Alex S.
    Tkachenko, Sergey E.
    Balakin, Konstantin V.
    Ivachtchenko, Alexandre V.
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2007, 11 (08) : 1087 - 1101
  • [10] A small-molecule antagonist of the hedgehog signaling pathway
    Lee, Jongkook
    Wu, Xu
    di Magliano, Marina Pasca
    Peters, Eric C.
    Wang, Yan
    Hong, Jiyong
    Hebrok, Metthias
    Din, Sheng
    Cho, Charles Y.
    Schultz, Peter G.
    CHEMBIOCHEM, 2007, 8 (16) : 1916 - +