Brain weight-body weight ratio in sudden infant death syndrome revisited

被引：10

作者：

Elliott, Jane A. ^{[1
]}

Vink, Robert ^{[1
]}

Jensen, Lisbeth ^{[1
]}

Byard, Roger W. ^{[1
]}

机构：

[1] Univ Adelaide, Discipline Anat & Pathol, Adelaide, SA 5000, Australia

来源：

MEDICINE SCIENCE AND THE LAW | 2012年 / 52卷 / 04期

关键词：

ORGAN WEIGHTS; GROWTH;

D O I：

10.1258/msl.2012.011136

中图分类号：

D9 [法律]; DF [法律];

学科分类号：

0301 ;

摘要：

Aims: To determine whether the brain-body weight ratio is increased in sudden infant death syndrome (SIDS). Methods: Review of autopsy files from Forensic Science SA, South Australia was undertaken over an eight-year period from 1999 to 2006, with classification of cases according to the San Diego definition. Sudden and/or unexpected deaths in previously healthy infants due to asphyxia or infection were selected as controls. Results: There were 42 SIDS cases and 25 controls. The SIDS cases were aged from 1 to 42 weeks (mean: 16.26 +/- 1.5 weeks) with a male to female ratio of 26:16. The control infants were aged from 3 to 48 weeks (mean: 19.24 +/- 2.9 weeks) (P > 0.05) (M:F = 16:9) and included 13 cases of asphyxia and 12 cases of sepsis. Comparison of the brain-body weight ratios failed to demonstrate a significant difference: SIDS mean = 0.121 +/- 0.003; control mean = 0.115 +/- 0.003 (P > 0.05). Conclusion: Although, there was a trend towards higher brain-body weight ratios in SIDS infants, this did not reach significance. The role of brain weight in the aetiology of SIDS remains controversial. Med Sci Law 2012; 52: 207-209. DOI: 10.1258/msl.2012.011136

引用

页码：207 / 209

页数：3

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