Determination of sub-ppb cadmium in urine by solid-phase extraction and inductively coupled plasma-mass spectrometry

被引：30

作者：

Suzuki, Yoshihiro ^{[1
]}

Endo, Yoko ^{[1
]}

Ogawa, Masanori ^{[1
]}

Matsuda, Michiko ^{[1
]}

Nakajima, Yoshiaki ^{[1
]}

Onda, Nobuhiko ^{[1
]}

Iwasaki, Motoki ^{[2
]}

Tsugane, Shoichiro ^{[2
]}

机构：

[1] Tokyo Rosai Occupat Dis & Injuries Hosp, Japan Labour Hlth & Welfare Org, Res Ctr Occupat Poisoning, Tokyo 1430013, Japan

[2] Natl Canc Ctr, Res Ctr Canc Prevent & Screening, Epidemiol & Prevent Div, Tokyo 1040045, Japan

来源：

ANALYTICAL SCIENCES | 2008年 / 24卷 / 08期

关键词：

D O I：

10.2116/analsci.24.1049

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In order to determine low levels of Cd in urine samples, we tried to remove Mo interference using ICP-MS with a dynamic reaction-cell technique, but failed due to the low sensitivity and the variance with the standards. We then performed solid-phase extraction (SPE) before the ICP-MS measurement. A commercially available chelating resin, NOBIAS PA-1, was used for SPE, and could effectively remove Mo from urine samples, permitting the accurate determination of Cd by ICP-MS. This SPE-ICP-MS method gave 0.012 mu g Cd L-1 as the method limit of quantification, and the mean recovery of Cd spiked with 0.0505 and 5.05 mu g L-1 was 93.1 and 97.6%, respectively.

引用

页码：1049 / 1052

页数：4

共 17 条

[1]

*CDCP, 2005, 3 NAT REP HUM EXP EN

[2] Bandpass reaction cell inductively coupled plasma mass spectrometry for the determination of silver and cadmium in samples in the presence of excess Zr, Nb and Mo [J].