Electrophilic substitution of indoles catalyzed by triphenyl phosphonium perchlorate:: Synthesis of 3-acetyl indoles and bis-indolylmethane derivatives

被引：73

作者：

Nagarajan, R ^{[1
]}

Perumal, PT ^{[1
]}

机构：

[1] Cent Leather Res Inst, Div Organ Chem, Chennai 600020, Tamil Nadu, India

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 01期

关键词：

D O I：

10.1081/SCC-120001515

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Triphenyl phosphonium perchlorate (TPP) is found to catalyze the acetylation of indoles with acetic anhydride to give 3-acetyl indoles. Similarly bis-indolylmethane derivatives were prepared by the electrophilic substitution reaction of indole with substituted benzaldehydes.

引用

页码：105 / 109

页数：5

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