The role of Haemophilus influenzae type b in fatal community-acquired pneumonia in Chinese children

被引：11

作者：

Hu, Huili ^{[1
,2
]}

He, Lejian ^{[3
]}

Dmitriev, Alexander ^{[4
]}

Hu, Yiyun ^{[1
]}

Deng, Jianghong ^{[1
]}

Zhang, Wenshaung ^{[1
]}

Yao, Kaihu ^{[1
]}

Yang, Yonghong ^{[1
,2
]}

机构：

[1] Capital Med Univ, Beijing Childrens Hosp, Lab Microbiol & Immunol, Dept Microbiol & Immunol, Beijing 100045, Peoples R China

[2] Capital Med Univ, Beijing Childrens Hosp, Dept Internal Med, Beijing 100045, Peoples R China

[3] Capital Med Univ, Beijing Childrens Hosp, Dept Pathol, Beijing 100045, Peoples R China

[4] Inst Expt Med, Dept Mol Microbiol, St Petersburg, Russia

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2008年 / 27卷 / 10期

关键词：

community-acquired pneumonia; fatal outcome; etiology; Haemophilus influenzae type b; in situ PCR; China;

D O I：

10.1097/INF.0b013e3181757b32

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To analyze the role of Haemophilus influenzae type b in children's death resulting from severe pneumonia conventional PCR, Southern blotting and in situ PCR were evaluated for the detection of Hib in 202 paraffin-embedded lung tissue autopsy samples from children with fatal outcome of pneumonia in China during the period of 1953-2002. The results indicate that Hib was a cause of fatal pneumonia in 36 (17.8%) of 202 samples.

引用

页码：942 / 944

页数：3

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