Babelomics 5.0: functional interpretation for new generations of genomic data

被引：91

作者：

Alonso, Roberto ^{[1
,2
]}

Salavert, Francisco ^{[1
,3
]}

Garcia-Garcia, Francisco ^{[1
]}

Carbonell-Caballero, Jose ^{[1
]}

Bleda, Marta ^{[4
]}

Garcia-Alonso, Luz ^{[1
]}

Sanchis-Juan, Alba ^{[5
]}

Perez-Gil, Daniel ^{[5
]}

Marin-Garcia, Pablo ^{[5
]}

Sanchez, Ruben ^{[1
,6
]}

Cubuk, Cankut ^{[1
]}

Hidalgo, Marta R. ^{[1
]}

Amadoz, Alicia ^{[1
]}

Hernansaiz-Ballesteros, Rosa D. ^{[1
]}

Aleman, Alejandro ^{[1
,3
]}

Tarraga, Joaquin ^{[1
]}

Montaner, David ^{[1
]}

Medina, Ignacio ^{[7
]}

Dopazo, Joaquin ^{[1
,2
,3
,6
]}

机构：

[1] Ctr Invest Principe Felipe CIPF, Computat Genom Dept, Valencia 46012, Spain

[2] Bull CIPF, Computat Genom Chair, Valencia 46012, Spain

[3] CIBER Enfermedades Raras CIBERER, Bioinformat Rare Dis BIER, Valencia 46012, Spain

[4] Univ Cambridge, Addenbrookes Hosp, Dept Med, Sch Clin Med, Cambridge CB2 0QQ, England

[5] Fdn Invest Clin Valencia INCLIVA, Valencia 46010, Spain

[6] CIPF, INB, Funct Genom Node, Valencia 46012, Spain

[7] Univ Cambridge, HPC Serv, Cambridge CB3 0RB, England

来源：

NUCLEIC ACIDS RESEARCH | 2015年 / 43卷 / W1期

关键词：

GENE-EXPRESSION DATA; WEB-BASED TOOL; MICROARRAY DATA-ANALYSIS; RNA-SEQ; SYSTEMS BIOLOGY; DIFFERENTIAL EXPRESSION; GEPAS; NETWORK; TRANSCRIPTOMICS; PATHWAYS;

D O I：

10.1093/nar/gkv384

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Babelomics has been running for more than one decade offering a user-friendly interface for the functional analysis of gene expression and genomic data. Here we present its fifth release, which includes support for Next Generation Sequencing data including gene expression (RNA-seq), exome or genome re-sequencing. Babelomics has simplified its interface, being now more intuitive. Improved visualization options, such as a genome viewer as well as an interactive network viewer, have been implemented. New technical enhancements at both, client and server sides, makes the user experience faster and more dynamic. Babelomics offers user-friendly access to a full range of methods that cover: (i) primary data analysis, (ii) a variety of tests for different experimental designs and (iii) different enrichment and network analysis algorithms for the interpretation of the results of such tests in the proper functional context. In addition to the public server, local copies of Babelomics can be downloaded and installed. Babelomics is freely available at: http://www.babelomics.org.

引用

页码：W117 / W121

页数：5

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