Evidence-based diabetes care for older people with Type 2 diabetes: a critical review

被引:65
作者
Sinclair, A. J. [1 ]
Abdelhafiz, A. H. [2 ]
Forbes, A. [3 ]
Munshi, M. [4 ,5 ]
机构
[1] Diabet Frail Ltd, Fdn Diabet Res Older People, Droitwich, England
[2] Rotherham Gen Hosp, Rotherham, S Yorkshire, England
[3] Kings Coll London, London, England
[4] Harvard Med Sch, Boston, MA 02115 USA
[5] Joslin Clin, Boston, MA 02115 USA
关键词
INTENSIVE GLUCOSE CONTROL; LIFE-STYLE INTERVENTION; POSITION STATEMENT; GLYCEMIC CONTROL; CARDIOVASCULAR OUTCOMES; ELDERLY-PATIENTS; DOUBLE-BLIND; WEIGHT-LOSS; MICROVASCULAR COMPLICATIONS; HYPOGLYCEMIC MEDICATIONS;
D O I
10.1111/dme.13859
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In our ageing society diabetes imposes a significant burden in terms of the numbers of people with the condition, diabetes-related complications including disability, and health and social care expenditure. Older people with diabetes can represent some of the more complex and difficult challenges facing the clinician working in different settings, and the recognition that we have only a relatively small (but increasing) evidence base to guide us in diabetes management is a limitation of our current approaches. Nevertheless, in this review we attempt to explore what evidence there is to guide us in a comprehensive scheme of treatment for older adults, often in a high-risk clinical state, in terms of glucose lowering, blood pressure and lipid management, frailty care and lifestyle interventions. We strive towards individualized care and make a call for action for more high-quality research using different trial designs.
引用
收藏
页码:399 / 413
页数:15
相关论文
共 99 条
[1]   Deintensification of hypoglycaemic medications-use of a systematic review approach to highlight safety concerns in older people with type 2 diabetes [J].
Abdelhafiz, A. H. ;
Sinclair, A. J. .
JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2018, 32 (04) :444-450
[2]   Frailty Among Community-Dwelling Elderly People in France: The Three-City Study [J].
Alberto Avila-Funes, Jose ;
Helmer, Catherine ;
Amieva, Helene ;
Barberger-Gateau, Pascale ;
Le Goff, Melanie ;
Ritchie, Karen ;
Portet, Florence ;
Carriere, Isabelle ;
Tavernier, Beatrice ;
Miguel Gutierrez-Robledo, Luis ;
Dartigues, Jean-Francois .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2008, 63 (10) :1089-1096
[3]   Physical Inactivity and Obesity Underlie the Insulin Resistance of Aging [J].
Amati, Francesca ;
Dube, John J. ;
Coen, Paul M. ;
Stefanovic-Racic, Maja ;
Toledo, Frederico G. S. ;
Goodpaster, Bret H. .
DIABETES CARE, 2009, 32 (08) :1547-1549
[4]   Older Adults: Standards of Medical Care in Diabetes-2018 [J].
不详 .
DIABETES CARE, 2018, 41 :S119-S125
[5]  
[Anonymous], AGE DORDR
[6]  
[Anonymous], NEW ENGL J MED
[7]  
[Anonymous], VADT 15 YEARS NO LEG
[8]  
[Anonymous], 2012, J AM GERIATR SOC
[9]   Long-term multiple risk factor interventions in Japanese elderly diabetic patients: The Japanese Elderly Diabetes Intervention Trial - study design, baseline characteristics and effects of intervention [J].
Araki, Atsushi ;
Iimuro, Satoshi ;
Sakurai, Takashi ;
Umegaki, Hiroyuki ;
Iijima, Katsuya ;
Nakano, Hiroshi ;
Oba, Kenzo ;
Yokono, Koichi ;
Sone, Hirohito ;
Yamada, Nobuhiro ;
Ako, Junya ;
Kozaki, Koichi ;
Miura, Hisayuki ;
Kashiwagi, Atsunori ;
Kikkawa, Ryuichi ;
Yoshimura, Yukio ;
Nakano, Tadasumi ;
Ohashi, Yasuo ;
Ito, Hideki .
GERIATRICS & GERONTOLOGY INTERNATIONAL, 2012, 12 :7-17
[10]   Use of Intensive Glycemic Management in Older Adults with Diabetes Mellitus [J].
Arnold, Suzanne V. ;
Lipska, Kasia J. ;
Wang, Jingyan ;
Seman, Leo ;
Mehta, Sanjeev N. ;
Kosiborod, Mikhail .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2018, 66 (06) :1190-1194