Detection of male breast cancer with Tc-99m methoxyisobutyl isonitrile

Carcinoma of the male breast is an uncommon disease, with an estimated 900 new cases diagnosed annually in the United States, and 300 deaths each year. It usually occurs in advanced age (mean age, 60 to 70 years). Infiltrating ductal carcinoma is the most common tumor type. The authors report a case of a 75-year-old man with a right breast mass diagnosed with sestamibi scintimammography. Mammographic diagnosis was unilateral gynecomastia. The Tc-99m MIBI study was found to be positive for malignancy. Surgical pathologic analysis revealed infiltrating ductal carcinoma.