Trends in Nanomaterials and Processing for Drug Delivery of Polyphenols in the Treatment of Cancer and Other Therapies

被引:10
作者
Ciurana, Joaquim [1 ]
Rodriguez, Ciro A. [2 ]
机构
[1] Univ Girona, Dept Mech Engn & Civil Construct, C Maria Aurelia Capmany 61, Girona 17003, Spain
[2] Ctr Innovac Diseno & Tecnol, Tecnol Monterrey, Av Eugenio Garza Sada 2501, Monterrey 64849, Nuevo Leon, Mexico
关键词
Drug deliver; polyphenols; nanocapsules; nanofibers; NANOFIBROUS SCAFFOLDS; TEA POLYPHENOLS; POLYMERIC NANOPARTICLES; CHITOSAN NANOPARTICLES; IN-VITRO; ELECTROSPUN; COMPOSITE; GELATIN; COLLAGEN; SYSTEMS;
D O I
10.2174/1389450116666151102094738
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
For decades polyphenols have been considered to be sound, naturally occurring therapeutic compounds. While there are several polyphenols with special applications used in the treatment of cancer and other diseases, they need a specific carrier in order to reach the cells targeted for treatment. Recently, a number of new technologies have been developed on a nanoscale, such as nanoparticles, nanocapsules and nanofibers that can provide targeted delivery of polyphenols for medical purposes. This work summarizes the current trends in nanoscale delivery technology for polyphenols in cancer treatment and outlines its capabilities and the significant improvements that have been made. Special emphasis is given to the materials and to the manufacturing processes used to produce these kinds of drug delivery system nanostructures.
引用
收藏
页码:135 / 146
页数:12
相关论文
共 91 条
[1]  
[Anonymous], J R SOC INTERFACE
[2]   Targeting Cancer with Nano-Bullets: Curcumin, EGCG, Resveratrol and Quercetin on Flying Carpets [J].
Aras, Aliye ;
Khokhar, Abdur Rehman ;
Qureshi, Muhammad Zahid ;
Silva, Marcela Fernandes ;
Sobczak-Kupiec, Agnieszka ;
Gomez Pineda, Edgardo Alfonso ;
Winkler Hechenleitner, Ana Adelina ;
Farooqi, Ammad Ahmad .
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (09) :3865-3871
[3]  
Barnes CP, 2006, J ENG FIBER FABR, V1, P16
[4]   Engineering of phosphatidylcholine-based solid lipid nanocarriers for flavonoids delivery [J].
Bazylinska, Urszula ;
Pucek, Agata ;
Sowa, Michal ;
Matczak-Jon, Ewa ;
Wilk, Kazimiera A. .
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2014, 460 :483-493
[5]   Polymer nanofibrous structures: Fabrication, biofunctionalization, and cell interactions [J].
Beachley, Vince ;
Wen, Xuejun .
PROGRESS IN POLYMER SCIENCE, 2010, 35 (07) :868-892
[6]   Polymeric nanoparticle-encapsulated curcumin (nanocurcumin"): A novel strategy for human cancer therapy" [J].
Bisht S. ;
Feldmann G. ;
Soni S. ;
Ravi R. ;
Karikar C. ;
Maitra A. ;
Maitra A. .
Journal of Nanobiotechnology, 5 (1)
[7]   Dual Fatty Acid Synthase and HER2 Signaling Blockade Shows Marked Antitumor Activity against Breast Cancer Models Resistant to Anti-HER2 Drugs [J].
Blancafort, Adriana ;
Giro-Perafita, Ariadna ;
Oliveras, Gloria ;
Palomeras, Sonia ;
Turrado, Carlos ;
Campuzano, Oscar ;
Carrion-Salip, Dolors ;
Massaguer, Anna ;
Brugada, Ramon ;
Palafox, Marta ;
Gomez-Miragaya, Jorge ;
Gonzalez-Suarez, Eva ;
Puig, Teresa .
PLOS ONE, 2015, 10 (06)
[8]   Electrospraying of polymers with therapeutic molecules: State of the art [J].
Bock, N. ;
Dargaville, T. R. ;
Woodruff, M. A. .
PROGRESS IN POLYMER SCIENCE, 2012, 37 (11) :1510-1551
[9]   Effects of a herbal gel containing carvacrol and chalcones on alveolar bone resorption in rats on experimental periodontitis [J].
Botelho, Marco Antonio ;
Rao, Vietla Satyanarayana ;
Montenegro, Danusa ;
Menezes Bandeira, Mary Anne ;
Cruz Fonseca, Said Goncalves ;
Pinto Nogueira, Nadia Accioly ;
Ribeiro, Ronaldo Albuquerque ;
Castro Brito, Gerly Anne .
PHYTOTHERAPY RESEARCH, 2008, 22 (04) :442-449
[10]   Electrospinning of collagen and elastin for tissue engineering applications [J].
Buttafoco, L ;
Kolkman, NG ;
Engbers-Buijtenhuijs, P ;
Poot, AA ;
Dijkstra, PJ ;
Vermes, I ;
Feijen, J .
BIOMATERIALS, 2006, 27 (05) :724-734