CAN TRANSPORTER-EXPRESSING CELLS PREDICT ROSUVASTATIN UPTAKE CLEARANCE IN SUSPENDED OR PLATED HUMAN HEPATOCYTES?

被引：0
|
作者：
Kumar, Vineet [1 ]
Salphati, Laurent [2 ]
Hop, Cornelis E. C. A. [2 ]
Rowbottom, Christopher [3 ]
Xiao, Guangqing [3 ]
Lai, Yurong [4 ]
Mathias, Anita [4 ]
Chu, Xiaoyan [5 ]
Humphreys, W. Griffith [6 ]
Liao, Mingxiang [7 ]
Chen, Laigao [8 ]
Toth, Beata [9 ]
Juhasz, Viktoria [9 ]
Heyward, Scott [10 ]
Unadkat, Jashvant
机构：
[1] Univ Washington, Seattle, WA 98195 USA
[2] Genentech Inc, San Francisco, CA USA
[3] Biogen Inc, 14 Cambridge Ctr, Cambridge, MA 02142 USA
[4] Gilead Sci Inc, Foster City, CA 94404 USA
[5] Merck & Co Inc, Kenilworth, NJ USA
[6] Bristol Myers Squibb, New York, NY USA
[7] Takeda Pharmaceut Int Inc, Deerfield, IL USA
[8] Pfizer Inc, New York, NY USA
[9] SOLVO Biotechnol, San Francisco, CA USA
[10] BioIVT, Westbury, NY USA
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2019年 / 34卷 / 01期
关键词：
D O I：
10.1016/j.dmpk.2018.09.094
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P11
引用
收藏
页码：S22 / S23
页数：2
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