Gingival Langerhans' cells in type I diabetes mellitus

被引：0
|
作者：
Gunhan, M [1 ]
Gunhan, O [1 ]
Celasun, B [1 ]
Azal, O [1 ]
Bostanci, H [1 ]
机构：
[1] GULHANE MIL MED SCH,DEPT PATHOL,ETLIK,TURKEY
来源：
JOURNAL OF PERIODONTOLOGY | 1996年 / 67卷 / 01期
关键词：
diabetes mellitus; insulin-dependent; Langerhans' cells; gingivitis etiology;
D O I：
暂无
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
LANGERKANS' CELLS (LCS) ARE INTRAEPITHELIAL immunocompetent cells. Changes in the number of LCs occur in inflammatory and autoimmune diseases. In this study, the number of gingival LCs in patients with type I diabetes mellitus was compared with those of normal individuals using immunohistochemical methods. Gingival biopsies were obtained from 20 type I diabetics and 10 healthy individuals. Anti-CD1 positive LCs formed an intraepithelial network and showed a marked increase in type I diabetics. This increase was not related to diabetic age. The number of LCs was proportional to the density of subepithelial inflammatory cells. Our findings suggest that LCs may play a role in the development of diabetic gingivitis.
引用
收藏
页码：37 / 40
页数：4
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