Gingival Langerhans' cells in type I diabetes mellitus

被引：0
|
作者：
Gunhan, M [1 ]
Gunhan, O [1 ]
Celasun, B [1 ]
Azal, O [1 ]
Bostanci, H [1 ]
机构：
[1] GULHANE MIL MED SCH,DEPT PATHOL,ETLIK,TURKEY
来源：
JOURNAL OF PERIODONTOLOGY | 1996年 / 67卷 / 01期
关键词：
diabetes mellitus; insulin-dependent; Langerhans' cells; gingivitis etiology;
D O I：
暂无
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
LANGERKANS' CELLS (LCS) ARE INTRAEPITHELIAL immunocompetent cells. Changes in the number of LCs occur in inflammatory and autoimmune diseases. In this study, the number of gingival LCs in patients with type I diabetes mellitus was compared with those of normal individuals using immunohistochemical methods. Gingival biopsies were obtained from 20 type I diabetics and 10 healthy individuals. Anti-CD1 positive LCs formed an intraepithelial network and showed a marked increase in type I diabetics. This increase was not related to diabetic age. The number of LCs was proportional to the density of subepithelial inflammatory cells. Our findings suggest that LCs may play a role in the development of diabetic gingivitis.
引用
收藏
页码：37 / 40
页数：4
相关论文
共 50 条
  • [1] Collagenases in gingival crevicular fluid in type 1 diabetes mellitus
    Safkan-Seppala, Bedia
    Sorsa, Timo
    Tervahartiala, Taina
    Beklen, Arzu
    Konttinen, Yrjo T.
    JOURNAL OF PERIODONTOLOGY, 2006, 77 (02) : 189 - 194
  • [2] The influence of type I diabetes mellitus in periodontal disease induced changes of the gingival epithelium and connective tissue
    Silva, J. A. F.
    Lorencini, M.
    Reis, J. R. R.
    Carvalho, H. F.
    Cagnon, V. H. A.
    Stach-Machado, D. R.
    TISSUE & CELL, 2008, 40 (04): : 283 - 292
  • [3] Role of Stem Cells in the Management of Type-I Diabetes Mellitus
    Arjun, H. R.
    Halagali, Praveen
    Tausi, Y. Mohammed
    Paramakrishnan, N.
    Rakshith, U. R.
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2023, 57 (04) : 951 - 955
  • [4] PERIVASCULAR CELLS OF FETOPLACENTAL VESSELS IN PREGNANCIES COMPLICATED BY TYPE I DIABETES MELLITUS
    Kucera, T.
    Vyletel, I.
    Moravcova, M.
    Krejci, V.
    Zizka, Z.
    Jirkovska, M.
    PLACENTA, 2010, 31 (09) : A35 - A35
  • [5] Islet transplantation in type I diabetes mellitus
    Gerber, P. A.
    Lehmann, R.
    DIABETOLOGE, 2015, 11 (07): : 545 - 552
  • [6] Novel therapies in the management of type I diabetes mellitus
    Ludvigsson, J.
    PANMINERVA MEDICA, 2012, 54 (04) : 257 - 270
  • [7] Imaging of the brain in children with type I diabetes mellitus
    Wootton-Gorges, Sandra L.
    Glaser, Nicole S.
    PEDIATRIC RADIOLOGY, 2007, 37 (09) : 863 - 869
  • [8] Seasonality of presentation of type I diabetes mellitus in children
    Douglas, S
    McSporran, B
    Smail, P
    SCOTTISH MEDICAL JOURNAL, 1999, 44 (02) : 41 - 46
  • [9] Vaccinations as risk factors for Type I diabetes mellitus
    Diabetologia, 2000, 43 (5) : A684 - A684
  • [10] Imaging of the brain in children with type I diabetes mellitus
    Sandra L. Wootton-Gorges
    Nicole S. Glaser
    Pediatric Radiology, 2007, 37 : 863 - 869
12345