The role of ARF and Rab GTPases in membrane transport

被引：432
作者：
Chavrier, P
Goud, B
机构：
[1] Ctr Immunol, INSERM, CNRS Marseille Luminy, F-13288 Marseille 9, France
[2] Inst Curie, CNRS UMR 144, Lab Mecanismes Mol Transport Intracellulaire, F-75248 Paris, France
来源：
CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 04期
关键词：
D O I：
10.1016/S0955-0674(99)80067-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Two key events of intracellular transport and membrane trafficking in eukaryotic cells, the formation of transport vesicles and their specific delivery to target membranes, are controlled by small GTPases of the ADP-ribosylation factor (ARF) and Rab families, respectively. The past 18 months have seen the identification of proteins that regulate ARF and Rab GDP/GTP cycle, as well as the characterization of their effecters, shedding light on the molecular mechanisms of ARF and Rab function.
引用
收藏
页码：466 / 475
页数：10
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