Biosensing and Probing of Intracellular Metabolic Pathways by NADH-Sensitive Quantum Dots

被引：112
作者：
Freeman, Ronit
Gill, Ron
Shweky, Itzhak
Kotler, Moshe
Banin, Uri
Willner, Itamar [1 ]
机构：
[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 02期
基金：
以色列科学基金会;
关键词：
biosensors; enzymes; nanobiotechnology; nanoparticles; quantum dots; RESONANCE ENERGY-TRANSFER; NAD(P)(+)-DEPENDENT ENZYMES; AMPEROMETRIC BIOSENSORS; NAD(P)H COFACTORS; ELECTRODES; NANOPARTICLES; SENSORS; TRANSFORMATIONS; NANOCRYSTALS;
D O I：
10.1002/anie.200803421
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) On the blue Nile: NAD(P)H-sensitive Nile Blue functionalized CdSe/ZnS quantum dots have been developed for the optical sensing of biocatalytic processes involving NAD+-dependent enzymes and the screening of anticancer drugs by monitoring intracellular metabolism (see picture). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：309 / 313
页数：5
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