Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H22 Cells in Mice

被引:3
|
作者
Fan, Yanli [1 ]
Wang, Wenhang [1 ]
Hu, Yuanshu [1 ]
Rong, Qi [1 ]
Teng, Anguo [1 ]
Liu, Anjun [1 ]
机构
[1] Tianjin Univ Sci & Technol, Minist Educ, Key Lab Food Nutr & Safety, Tianjin 300457, Peoples R China
关键词
tea polysaccharides; tea polyphenols; anti-tumor; splenocyte proliferation; macrophage phagocytosis; GREEN TEA;
D O I
10.4028/www.scientific.net/AMR.690-693.1193
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The effects of tea polysaccharides (TPS) and polyphenols (TPP) on the growth inhibition of hepatoma H22 cells in mice including the roles of them in immune stimulation were investigated. The results showed that TPS and TPP both significantly inhibited the growth of H22 transplantable tumor in mice without statistical difference, both remarkably decreased the spleen index and increased the thymus index compared with that of model group (p<0.05). In addition, TPS and TPP significantly improved the splenocyte proliferation induced by ConA or LPS, and notably enhanced the macrophage phagocytosis towards neutral red. The comparison showed the effect of TPS on immune stimulation was superior to that of TPP to some extent.
引用
收藏
页码:1193 / 1197
页数:5
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