Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H22 Cells in Mice

被引:3
作者
Fan, Yanli [1 ]
Wang, Wenhang [1 ]
Hu, Yuanshu [1 ]
Rong, Qi [1 ]
Teng, Anguo [1 ]
Liu, Anjun [1 ]
机构
[1] Tianjin Univ Sci & Technol, Minist Educ, Key Lab Food Nutr & Safety, Tianjin 300457, Peoples R China
来源
MATERIAL DESIGN, PROCESSING AND APPLICATIONS, PARTS 1-4 | 2013年 / 690-693卷
关键词
tea polysaccharides; tea polyphenols; anti-tumor; splenocyte proliferation; macrophage phagocytosis; GREEN TEA;
D O I
10.4028/www.scientific.net/AMR.690-693.1193
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The effects of tea polysaccharides (TPS) and polyphenols (TPP) on the growth inhibition of hepatoma H22 cells in mice including the roles of them in immune stimulation were investigated. The results showed that TPS and TPP both significantly inhibited the growth of H22 transplantable tumor in mice without statistical difference, both remarkably decreased the spleen index and increased the thymus index compared with that of model group (p<0.05). In addition, TPS and TPP significantly improved the splenocyte proliferation induced by ConA or LPS, and notably enhanced the macrophage phagocytosis towards neutral red. The comparison showed the effect of TPS on immune stimulation was superior to that of TPP to some extent.
引用
收藏
页码:1193 / 1197
页数:5
相关论文
共 13 条
[1]  
ALAM N, 1986, PLANTA MED, P308, DOI 10.1055/s-2007-969161
[2]   Antitumor and immunomodulatory activity of arabinoxylans: A major constituent of wheat bran [J].
Cao, Li ;
Liu, Xiuzhen ;
Qian, Tianxiu ;
Sun, Guibo ;
Guo, Yan ;
Chang, Fengjin ;
Zhou, Sumei ;
Sun, Xiaobo .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2011, 48 (01) :160-164
[3]   Tea polyphenols and their roles in cancer prevention and chemotherapy [J].
Chen, Di ;
Dou, Q. Ping .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2008, 9 (07) :1196-1206
[4]   Physicochemical characterization and antioxidant activity of a polysaccharide isolated from oolong tea [J].
Chen, Haixia ;
Wang, Zhaoshuai ;
Qu, Zhishuang ;
Fu, Lingling ;
Dong, Peng ;
Zhang, Xin .
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2009, 229 (04) :629-635
[5]  
Chen ZY, 1998, J AM OIL CHEM SOC, V75, P1141, DOI 10.1007/s11746-998-0303-5
[6]   Orally administered mycelial culture of Phellinus linteus exhibits antitumor effects in hepatoma cell-bearing mice [J].
Huang, Hui-Yu ;
Chieh, Shih-Yung ;
Tso, Tim K. ;
Chien, Ting-Yi ;
Lin, Hsin-Tang ;
Tsai, Ying-Chieh .
JOURNAL OF ETHNOPHARMACOLOGY, 2011, 133 (02) :460-466
[7]   Cancer and metastasis: prevention and treatment by green tea [J].
Khan, Naghma ;
Mukhtar, Hasan .
CANCER AND METASTASIS REVIEWS, 2010, 29 (03) :435-445
[8]   Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis [J].
Kim, Hye Kyung ;
Yang, Taik-Hoon ;
Cho, Hong-Yon .
WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (41) :5200-5205
[9]   In vitro antioxidative and anticancer activities of tea glycoprotein in green tea [J].
Nie, Shaoping ;
Xie, Mingyong ;
Zhou, Peng ;
Cao, Shuwen .
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2007, 224 (04) :437-442
[10]   Antioxidant activities of crude tea polyphenols, polysaccharides and proteins of selenium-enriched tea and regular green tea [J].
Yu, Fang ;
Sheng, Jianchun ;
Xu, Juan ;
An, Xinxin ;
Hu, Qiuhui .
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2007, 225 (5-6) :843-848