Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H22 Cells in Mice

被引:3
|
作者
Fan, Yanli [1 ]
Wang, Wenhang [1 ]
Hu, Yuanshu [1 ]
Rong, Qi [1 ]
Teng, Anguo [1 ]
Liu, Anjun [1 ]
机构
[1] Tianjin Univ Sci & Technol, Minist Educ, Key Lab Food Nutr & Safety, Tianjin 300457, Peoples R China
关键词
tea polysaccharides; tea polyphenols; anti-tumor; splenocyte proliferation; macrophage phagocytosis; GREEN TEA;
D O I
10.4028/www.scientific.net/AMR.690-693.1193
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The effects of tea polysaccharides (TPS) and polyphenols (TPP) on the growth inhibition of hepatoma H22 cells in mice including the roles of them in immune stimulation were investigated. The results showed that TPS and TPP both significantly inhibited the growth of H22 transplantable tumor in mice without statistical difference, both remarkably decreased the spleen index and increased the thymus index compared with that of model group (p<0.05). In addition, TPS and TPP significantly improved the splenocyte proliferation induced by ConA or LPS, and notably enhanced the macrophage phagocytosis towards neutral red. The comparison showed the effect of TPS on immune stimulation was superior to that of TPP to some extent.
引用
收藏
页码:1193 / 1197
页数:5
相关论文
共 50 条
  • [1] Inhibitory effect of eucheuma gelatinae polysaccharides on H22 hepatoma xenograft cells
    Tang, Juan
    Kong, Zhen
    Ji, Hai-Yu
    Liu, An-Jun
    Modern Food Science and Technology, 2015, 31 (01) : 1 - 5
  • [2] Anti-hepatoma activity and mechanism of corn silk polysaccharides in H22 tumor-bearing mice
    Yang, Jingyue
    Li, Xiao
    Xue, Yan
    Wang, Nan
    Liu, Wenchao
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2014, 64 : 276 - 280
  • [3] Immunoregulatory activity of polysaccharides from Tanyang Congou black tea on H22 tumor-bearing mice
    Hai-yu Ji
    Xiao-dan Dong
    Sha-sha Yu
    Juan Yu
    Ying-ying Feng
    An-jun Liu
    Journal of Food Measurement and Characterization, 2019, 13 : 1620 - 1626
  • [4] Immunoregulatory activity of polysaccharides from Tanyang Congou black tea on H22 tumor-bearing mice
    Ji, Hai-yu
    Dong, Xiao-dan
    Yu, Sha-sha
    Yu, Juan
    Feng, Ying-ying
    Liu, An-jun
    JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, 2019, 13 (02) : 1620 - 1626
  • [5] Polysaccharides from the peels of Citrus aurantifolia induce apoptosis in transplanted H22 cells in mice
    Zhao, Yana
    Sun, Hongyan
    Ma, Ling
    Liu, Anjun
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 101 : 680 - 689
  • [6] Influence of polysaccharides from angelica and astragalus on H22 hepatocarcinoma mice
    Pu, X., 1600, Journal of Chemical and Pharmaceutical Research, 3/668 Malviya Nagar, Jaipur, Rajasthan, India (06):
  • [7] Effect of luteolin on gene expression in mouse H22 hepatoma cells
    Niu, J. X.
    Guo, H. P.
    Gan, H. M.
    Bao, L. D.
    Ren, J. J.
    GENETICS AND MOLECULAR RESEARCH, 2015, 14 (04): : 14448 - 14456
  • [8] Astaxanthin Inhibits Proliferation and Induces Apoptosis and Cell Cycle Arrest of Mice H22 Hepatoma Cells
    Shao, Yiye
    Ni, Yanbo
    Yang, Jing
    Lin, Xutao
    Li, Jun
    Zhang, Lixia
    MEDICAL SCIENCE MONITOR, 2016, 22 : 2152 - 2160
  • [9] Induction of interleukin 2 expression in the liver for the treatment of H22 hepatoma in mice
    Cheng, Wei
    Miao, Lanfang
    Zhang, Haiying
    Yang, Ou
    Ge, He
    Li, Yanru
    Wang, Lin
    DIGESTIVE AND LIVER DISEASE, 2013, 45 (01) : 50 - 57
  • [10] Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro
    Qing E Tian
    Huan De Li
    Miao Yan
    Hua-Lin Cai
    Qin-You Tan
    Wen-Yuan Zhang
    BMC Complementary and Alternative Medicine, 12