Multifocal Amelanotic Melanoma of the Hard Palate: A Challenging Case

被引:17
作者
Limongelli, Luisa [1 ]
Cascardi, Eliano [2 ]
Capodiferro, Saverio [1 ]
Favia, Gianfranco [1 ]
Corsalini, Massimo [1 ]
Tempesta, Angela [1 ]
Maiorano, Eugenio [2 ]
机构
[1] Univ Bari Aldo Moro, Dept Interdisciplinary Med, Piazza G Cesare 11, I-70124 Bari, Italy
[2] Univ Bari Aldo Moro, Dept Emergency & Organ Transplantat, Piazza G Cesare 11, I-70124 Bari, Italy
关键词
melanoma; head and neck; oral tumors; mucosal melanoma; MALIGNANT-MELANOMA; ORAL MELANOMA; METASTATIC MELANOMA; CAVITY; HEAD; EXPRESSION; DIAGNOSIS;
D O I
10.3390/diagnostics10060424
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Among all melanomas, the mucosal type is very rare and may occur in the sino-nasal mucosa, vagina, anus and the oral cavity. At variance with melanomas of the skin, no risk factors, such as familiarity, UV-exposure and skin phenotype, have been clearly identified for such neoplasms. Frequently, the diagnosis is delayed and achieved at advanced stages or when metastases have already occurred. The authors report on a case of mucosal melanoma of the oral cavity presenting as a mass of the hard palate in a 50-year old male, and the corresponding diagnostic-therapeutic pathway.
引用
收藏
页数:9
相关论文
共 25 条
[1]   Mucosal melanoma of the head and neck [J].
Ascierto, Paolo Antonio ;
Accorona, Remo ;
Botti, Gerardo ;
Farina, Davide ;
Fossati, Piero ;
Gatta, Gemma ;
Gogas, Helen ;
Lombardi, Davide ;
Maroldi, Roberto ;
Nicolai, Piero ;
Ravanelli, Marco ;
Vanella, Vito .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2017, 112 :136-152
[2]   Metastatic melanoma mimicking solitary fibrous tumor: report of two cases [J].
Bekers, Elise M. ;
van Engen-van Grunsven, Adriana C. H. ;
Groenen, Patricia J. T. A. ;
Westdorp, Harm ;
Koornstra, Rutger H. T. ;
Bonenkamp, Johannes J. ;
Flucke, Uta ;
Blokx, Willeke A. M. .
VIRCHOWS ARCHIV, 2014, 464 (02) :247-251
[3]  
Brierley JD., 2017, TNM CLASSIFICATION M, P45
[4]  
Crowson AN, 2002, RECENT RES CANCER, V160, P75
[5]   Commentary on "Oral melanoma and other pigmentations: when to biopsy?' [J].
De Piano, E. ;
Cinotti, E. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2018, 32 (10) :E398-E399
[6]   Primary oral melanoma: A histopathological and immunohistochemical study of 22 cases of Latin America [J].
de-Andrade, Bruno-Augusto-Benevenuto ;
Toral-Rizo, Victor-Hugo ;
Leon, Jorge-Esquiche ;
Contreras, Elisa ;
Carlos, Roman ;
Delgado-Azanero, Wilson ;
Mosqueda-Taylor, Adalberto ;
de-Almeida, Oslei-Paes .
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, 2012, 17 (03) :E383-E388
[7]   Malignant melanoma of the oral cavity: Report of 14 cases from a regional cancer centre [J].
Doval, DC ;
Rao, CR ;
Sabitha, KS ;
Vigayakumar, M ;
Misra, S ;
Mani, K ;
Bapsy, PP ;
Kumaraswamy, SV .
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 1996, 22 (03) :245-249
[8]   ORAL MELANOMA AND OTHER PIGMENTED LESIONS OF THE ORAL CAVITY [J].
EISEN, D ;
VOORHEES, JJ .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1991, 24 (04) :527-537
[9]   Risk of melanoma in relation to smoking, alcohol intake, and other factors in a large occupational cohort [J].
Freedman, DM ;
Sigurdson, A ;
Doody, MM ;
Rao, RS ;
Linet, MS .
CANCER CAUSES & CONTROL, 2003, 14 (09) :847-857
[10]  
Gonzalez-Garcia Raul, 2005, Med Oral Patol Oral Cir Bucal, V10, P264