Intravenously Injected Recombinant Human Type VII Collagen Homes to Skin Wounds and Restores Skin Integrity of Dystrophic Epidermolysis Bullosa

被引：71

作者：

Woodley, David T. ^{[1
]}

Wang, Xinyi ^{[1
]}

Amir, Mahsa ^{[1
]}

Hwang, Brian ^{[1
]}

Remington, Jennifer ^{[1
]}

Hou, Yingpin ^{[1
]}

Uitto, Jouni ^{[2
]}

Keene, Douglas ^{[3
]}

Chen, Mei ^{[1
]}

机构：

[1] Univ So Calif, Dept Dermatol, Los Angeles, CA 90089 USA

[2] Thomas Jefferson Univ, Jefferson Med Coll, Dept Dermatol & Cutaneous Biol, Philadelphia, PA 19107 USA

[3] Shriners Hosp Children, Portland, OR 97201 USA

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2013年 / 133卷 / 07期

关键词：

ANCHORING FIBRILS; CORRECTS; FIBROBLASTS; PHENOTYPE; DISEASE; TISSUE; MODEL;

D O I：

10.1038/jid.2013.10

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：1910 / 1913

页数：4

共 16 条

[1] TYPE-VII COLLAGEN, ANCHORING FIBRILS, AND EPIDERMOLYSIS-BULLOSA [J].

BURGESON, RE .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1993, 101 (03) :252-255

[2] Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa [J].

Chen, M ;

Kasahara, N ;

Keene, DR ;

Chan, L ;

Hoeffler, WK ;

Finlay, D ;

Barcova, M ;

Cannon, PM ;

Mazurek, C ;

Woodley, DT .

NATURE GENETICS, 2002, 32 (04) :670-675

[3]

CHRISTIANO AM, 1994, J BIOL CHEM, V269, P20256

[4] The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB [J].

Fine, Jo-David ;

Eady, Robin A. J. ;

Bauer, Eugene A. ;

Bauer, Johann W. ;

Bruckner-Tuderman, Leena ;

Heagerty, Adrian ;

Hintner, Helmut ;

Hovnanian, Alain ;

Jonkman, Marcel E. ;

Leigh, Irene ;

McGrath, John A. ;

Mellerio, Jemima E. ;

Murrell, Dedee E. ;

Shimizu, Hiroshi ;

Uitto, Jouni ;

Vahlquist, Anders ;

Woodley, David ;

Zambruno, Giovanna .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2008, 58 (06) :931-950

[5]

Heinonen S, 1999, J CELL SCI, V112, P3641

[6] Stable nonviral genetic correction of inherited human skin disease [J].

Ortiz-Urda, S ;

Thyagarajan, B ;

Keene, DR ;

Lin, Q ;

Fang, M ;

Calos, MP ;

Khavari, PA .

NATURE MEDICINE, 2002, 8 (10) :1166-1170

[7] Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue [J].

Ortiz-Urda, S ;

Lin, Q ;

Green, CL ;

Keene, DR ;

Marinkovich, MP ;

Khavari, PA .

JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (02) :251-255

[8] Injection of Recombinant Human Type VII Collagen Corrects the Disease Phenotype in a Murine Model of Dystrophic Epidermolysis Bullosa [J].

Remington, Jennifer ;

Wang, Xinyi ;

Hou, Yingpin ;

Zhou, Hui ;

Burnett, Julie ;

Muirhead, Trevor ;

Uitto, Jouni ;

Keene, Douglas R. ;

Woodley, David T. ;

Chen, Mei .

MOLECULAR THERAPY, 2009, 17 (01) :26-33

[9]

SAELMAN EUM, 1994, BLOOD, V83, P1244

[10] TYPE-VII COLLAGEN IS A MAJOR STRUCTURAL COMPONENT OF ANCHORING FIBRILS [J].

SAKAI, LY ;

KEENE, DR ;

MORRIS, NP ;

BURGESON, RE .

JOURNAL OF CELL BIOLOGY, 1986, 103 (04) :1577-1586

← 1 2 →