Preparation and antimicrobial activity of quaternary phosphonium modified epoxidized natural rubber

被引：29

作者：

Li, Chun ^{[1
]}

Liu, Yuan ^{[2
]}

Zeng, Qiu-Yuan ^{[3
]}

Ao, Ning-Jian ^{[1
]}

机构：

[1] Jinan Univ, Dept Biomed Engn, Guangzhou 510632, Guangdong, Peoples R China

[2] Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China

[3] Sun Yat Sen Univ, Sch Engn, Guangzhou 510275, Guangdong, Peoples R China

来源：

MATERIALS LETTERS | 2013年 / 93卷

基金：

中国国家自然科学基金;

关键词：

Epoxidized natural rubber; Chemical modification; Permanent antimicrobial; Quaternary phosphonium salt; Functional; Biomaterials; POLYMERS; COPOLYMERS; AMMONIUM; SURFACES;

D O I：

10.1016/j.matlet.2012.11.045

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Natural rubber was commonly endowed with antimicrobial activity by adding low molecular weight biocidal agents. Herein we report a new antimicrobial rubber prepared by chemical modification. Quaternary phosphonium salt (QPs) groups were covalently immobilized onto the molecular chains of epoxidized natural rubber (ENR) using halogenated acid as an intermediary. The structures of modified rubbers were confirmed while the antimicrobial activity of QP modified ENR was investigated. Results show that the ring-opening ENR and the QP modified ENR are successfully prepared. The proliferation of microorganisms tested can be effectively inhibited by using QP modified ENR. Meanwhile, the modified ENR illustrates better antimicrobial activity toward Gram-negative E. coli than Gram-positive S. aureus. This method can provide potential applications in preparing permanent antimicrobial rubbers. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：145 / 148

页数：4

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