Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy

被引：40

作者：

Sanchez-Garcia, Ana B. ^{[1
]}

Galindo-Villardon, Purificacion ^{[2
]}

Nieto-Librero, Ana B. ^{[2
]}

Martin-Rodero, Helena ^{[3
]}

Robins, Diana L. ^{[4
]}

机构：

[1] Univ Salamanca, INICO, Pso Canalejas 169, E-37008 Salamanca, Spain

[2] Univ Salamanca, IBSAL, C Alfonso X El Sabio S-N, Salamanca 37007, Spain

[3] Univ Salamanca, Med Sch Lib, C Alfonso X El Sabio S-N, Salamanca 37007, Spain

[4] AJ Drexel Autism Inst, 3020 Market St,Suite 560, Philadelphia, PA 19104 USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2019年 / 49卷 / 05期

关键词：

M-CHAT; Autism; Screening tools; Meta-analysis; Systematic review; HSROC; MODIFIED CHECKLIST; YOUNG-CHILDREN; GENERAL-POPULATION; VALIDATION; SPECIFICITY; SENSITIVITY; QUALITY; CARE;

D O I：

10.1007/s10803-018-03865-2

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Great efforts focus on early detection of autism spectrum disorder, although some scientists and policy-makers have questioned early universal screening. The aim of this meta-analysis was to evaluate the diagnostic accuracy of the different screening tools. Several electronic databases were used to identify published studies. A Bayesian model was used to estimate the screening accuracy. The pooled sensitivity was 0.72 (95% CI 0.61-0.81), and the specificity was 0.98 (95% CI 0.97-0.99). Subgroup analyses to remove heterogeneity indicated sensitivity was 0.77 (95% CI 0.69-0.84), and specificity was 0.99 (95% CI 0.97-0.99; SD0.01). Level 1 screening tools for ASD showed consistent statistically significant results and therefore are adequate to detect autism at 14-36months.

引用

页码：1837 / 1852

页数：16

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