Reaction of pyridinium salts with active methylene compounds

被引：3
|
作者：
Fujita, R [1 ]
Hoshino, M [1 ]
Nishiuchi, Y [1 ]
Tomisawa, H [1 ]
机构：
[1] Tohoku Pharmaceut Univ, Aoba Ku, Sendai, Miyagi 9818558, Japan
来源：
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 2006年 / 126卷 / 02期
关键词：
1-methyl-2-methylthio-4-phenylpyridinium salt; dimethyl malonate; sodium hydride; 1-methyl-2methylthio-5-phenylpyridinium iodide; 1-methyl-2-methylthio-6-phenylpyridinium iodide; malononitrile;
D O I：
10.1248/yakushi.126.109
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The carbon-carbon bond-forming reactions of 1-methyl-2-methylthiophenylpyridinium iodides with active methylene compounds (such as dimethyl malonate, malononitrile) using NaH as a base gave the 2-substituted methylene-1,2dihydropyridine derivatives.
引用
收藏
页码：109 / 116
页数：8
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