Thymus catharinae Camarda essential oil: β-cyclodextrin inclusion complexes, evaluation of antimicrobial activity

被引：17

作者：

Delogu, Giovanna ^{[1
]}

Juliano, Claudia Clelia Assunta ^{[2
]}

Usai, Marianna ^{[3
]}

机构：

[1] CNR, Ist Chim Biomol, Traversa La Crucca, Li Punti Sassar, Italy

[2] Univ Sassari, Dipartimento Chim & Farm, Sassari, Italy

[3] Univ Sassari, Dipartimento Sci Nat & Terr, Sassari, Italy

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 18期

关键词：

Thymus catharinae Camarda; essential oil; carvacrol; antimicrobial; E; coli; C; albicans; cyclodextrin inclusion complex; HERBA-BARONA LOISEL; IN-VITRO; GROWING WILD; VARIABILITY; CARVACROL; LAMIACEAE; SARDINIA; H-1-NMR;

D O I：

10.1080/14786419.2015.1107558

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An efficient antimicrobial activity was evidenced in a complex -cyclodextrin-essential oil of Thymus catharinae Camarda (carvacrol chemotype). The release of carvacrol with respect to the antimicrobial activity was calculated as function of time. The CD-complex of the bioactive agent was obtained by a simple, efficient and non-expensive method without purification of the carvacrol chemotype essential oil. According to the starting stoichiometry of -cyclodextrin with respect to carvacrol, two inclusion complexes were produced, 1:1 and 2:1, respectively. The results demonstrate that, although the antimicrobial activity of the essential oil of T. catharinae Camarda is remarkable but acts too quickly in some types of application, its inclusion in a bio-matrix allows a slower release and improves its effectiveness. [GRAPHICS] .

引用

页码：2049 / 2057

页数：9

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