Age-Related Medicine

被引：11

作者：

Wahlich, John ^{[1
]}

Orlu, Mine ^{[2
]}

Mair, Alpana ^{[3
]}

Stegemann, Sven ^{[4
]}

van Riet-Nales, Diana ^{[5
]}

机构：

[1] Acad Pharmaceut Sci, 4 Heydon Rd, Royston SG8 8SR, Herts, England

[2] UCL, Sch Pharm, Dept Pharmaceut, 29-39 Brunswick Sq, London WC1N 1AX, England

[3] Scottish Govt, Hlth & Social Care Directorate, Effect Prescribing & Therapeut, Edinburgh EH6 5NL, Midlothian, Scotland

[4] Graz Univ Technol, Inst Proc & Particle Engn, Inffeldgasse 13, A-8010 Graz, Austria

[5] Medicines Evaluat Board Netherlands, Qual Dept, Chem Pharmaceut Assessments, POB 8275, NL-3503 RG Utrecht, Netherlands

来源：

PHARMACEUTICS | 2019年 / 11卷 / 04期

关键词：

polypharmacy; multiple morbidities; ageing; pharmaceutical sciences; product development; SIMPATHY; ADVERSE DRUG-REACTIONS; OLDER-PEOPLE; GERIATRIC MEDICINES; MULTIMORBIDITY; HEALTH; APPROPRIATENESS; FRAILTY; BASE; LIFE;

D O I：

10.3390/pharmaceutics11040172

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A meeting organised by the Academy of Pharmaceutical Sciences focussed on the challenges of developing medicines for older adults. International experts discussed the complexity introduced by polypharmacy and multiple morbidities and how the risk-benefit ratio of a medicine changes as an individual ages. The way in which regulatory authorities are encouraging the development of age-appropriate medicines was highlighted. Examples were provided of the difficulties faced by the older population with some medicinal products and suggestions given as to how the pharmaceutical scientist can build the requirements of the older population into their development of new medicines, as well as improvements to existing ones.

引用

页数：11

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