Hypercalcemia associated with adenosquamous pancreatic carcinoma: A reason to initiate palliative treatment

被引：0

作者：

Lopez-Tomassetti-Fernandez, Eudaldo M. ^{[1
]}

Favre-Rizzo, Julian ^{[1
]}

Delgado-Plasencia, Luciano ^{[2
]}

Ramon Hernandez-Hernandez, Juan ^{[1
]}

机构：

[1] Hosp Univ Insular Gran Canaria, Dept Gastrointestinal Surg, Las Palmas Gran Canaria 35016, Spain

[2] Hosp Univ Canarias, Dept Gastrointestinal Surg, Tenerife, Spain

来源：

REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS | 2013年 / 105卷 / 07期

关键词：

Adenosquamous carcinoma; Pancreatic malignancy; Humoral hypercalcemia; HORMONE-RELATED PROTEIN; CANCER; MALIGNANCY; ANTIBODY; CACHEXIA;

D O I：

10.4321/S1130-01082013000700009

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: hypercalcemia in patients with diagnosed carcinoma has predominantly a humoral basis mediated by parathyroid hormone-related protein (PTH-rP). Among the reported cases, hypercalcemia associated with the majority of abdominal malignancies indicates an advanced stage of disease. Case report: we present a case of a 78-year-old patient with an adenosquamous pancreatic carcinoma associated with humoral hypercalcemia mediated by PTH-rP. Conclusion: in this case, demonstration of unexpectantly rapid increase in calcium serum correlated with aggressive tumor growth led us to raise the hypothesis that PTH-rP could be a mediator of invasion and dissemination secreted by some tumors, and probably indicates the appropriate time to initiate palliative treatment.

引用

页码：425 / 428

页数：4

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