Copper catalysis at operando conditions-bridging the gap between single nanoparticle probing and catalyst-bed-averaging

In catalysis, nanoparticles enable chemical transformations and their structural and chemical fingerprints control activity. To develop understanding of such fingerprints, methods studying catalysts at realistic conditions have proven instrumental. Normally, these methods either probe the catalyst bed with low spatial resolution, thereby averaging out single particle characteristics, or probe an extremely small fraction only, thereby effectively ignoring most of the catalyst. Here, we bridge the gap between these two extremes by introducing highly multiplexed single particle plasmonic nanoimaging of model catalyst beds comprising 1000 nanoparticles, which are integrated in a nanoreactor platform that enables online mass spectroscopy activity measurements. Using the example of CO oxidation over Cu, we reveal how highly local spatial variations in catalyst state dynamics are responsible for contradicting information about catalyst active phase found in the literature, and identify that both surface and bulk oxidation state of a Cu nanoparticle catalyst dynamically mediate its activity. Characterizing individual catalyst nanoparticles at operando conditions is a cornerstone of catalysis research. Here the authors utilize plasmonic optical nanoimaging in a nanofluidic reactor to map the impact of reactor geometry on single Cu particle oxidation state dynamics and active phase during CO oxidation.