Initial assessment of tumor tracking with a gimbaled linac system in clinical circumstances: A patient simulation study

被引:78
作者
Depuydt, Tom [1 ,2 ]
Poels, Kenneth [1 ,2 ]
Verellen, Dirk [1 ,2 ]
Engels, Benedikt [1 ]
Collen, Christine [1 ]
Haverbeke, Chloe [1 ]
Gevaert, Thierry [1 ]
Buls, Nico [1 ,3 ]
Van Gompel, Gert [3 ]
Reynders, Truus [1 ]
Duchateau, Michael [1 ]
Tournel, Koen [1 ]
Boussaer, Marlies [1 ]
Steenbeke, Femke [1 ,2 ]
Vandenbroucke, Frederik [3 ]
De Ridder, Mark [1 ,2 ]
机构
[1] Vrije Univ Brussel, Dept Radiotherapy, B-1090 Brussels, Belgium
[2] Vrije Univ Brussel, Fac Med & Pharm, B-1090 Brussels, Belgium
[3] Vrije Univ Brussel, Dept Radiol, B-1090 Brussels, Belgium
关键词
Tumor tracking; Stereotactic body radiation therapy; Organ motion; RADIATION-THERAPY; MOTION; RADIOTHERAPY; CYBERKNIFE; ACCURACY; VOLUME;
D O I
10.1016/j.radonc.2012.12.015
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To have an initial assessment of the Vero Dynamic Tracking workflow in clinical circumstances and quantify the performance of the tracking system, a simulation study was set up on 5 lung and liver patients. Methods and materials: The preparatory steps of a tumor tracking treatment, based on fiducial markers implanted in the tumor, were executed allowing pursuit of the tumor with the gimbaled linac and monitoring X-rays acquisition, however, without activating the 6 MV beam. Data were acquired on workflow time-efficiency, tracking accuracy and imaging exposure. Results: The average time between the patient entering the treatment room and the first treatment field was about 9 min. The time for building the correlation model was 3.2 min. Tracking errors of 0.55 and 0.95 mm (1 sigma) were observed in PAN/TILT direction and a 2D range of 3.08 mm. A skin dose was determined of 0.08 mGy/image, with a source-to-skin distance of 900 mm and kV exposure of 1 mAs. On average 1.8 mGy/min kV skin dose was observed for 1 Hz monitoring. Conclusion: The Vero tracking solution proved to be fully functional and showed performance comparable with other real-time tracking systems. (C) 2013 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 106 (2013) 236-240
引用
收藏
页码:236 / 240
页数:5
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