Urban family cluster of spotted fever rickettsiosis linked to Rhipicephalus sanguineus infected with Rickettsia conorii subsp caspia and Rickettsia massiliae

被引：38

作者：

Renvoise, Aurelie ^{[1
]}

Delaunay, Pascal ^{[2
,3
]}

Blanchouin, Elea ^{[4
]}

Cannavo, Isabelle ^{[3
,5
]}

Cua, Eric ^{[4
]}

Socolovschi, Cristina ^{[1
]}

Parola, Philippe ^{[1
]}

Raoult, Didier ^{[1
]}

机构：

[1] Aix Marseille Univ, Fac Med, URMITE,UM63,CNRS 7278,IRD 198,Inserm 1095, WHO Collaborat Ctr Rickettsioses & Other Arthropo, F-13385 Marseille 5, France

[2] CHU Nice, Hop Archet, Serv Parasitol Mycol, Nice, France

[3] Univ Nice Sophia Antipolis, C3M, U895, INSERM, Nice, France

[4] CHU Nice, Hop Archet, Serv Infectiol, Nice, France

[5] CHU Nice, Hop Archet, Virol Lab, Nice, France

来源：

TICKS AND TICK-BORNE DISEASES | 2012年 / 3卷 / 5-6期

关键词：

Rickettsia conorii; Rhipicephalus sanguineus; France; Spotted fever; DERMACENTOR-VARIABILIS TICK; BROWN DOG TICK; OLD;

D O I：

10.1016/j.ttbdis.2012.10.008

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Here, we report an epidemiological and entomological investigation of a cluster of cases of spotted fever group (SFG) rickettsiosis occurring in southern France. A family of 3 (husband, wife, and their son) presented with symptoms compatible with SFG rickettsiosis. For 2 patients, serum samples presented increased levels of IgM and IgG for SFG Rickettsia. The patients' home was investigated, and Rhipicephalus sanguineus ticks were collected from the floor from behind the furniture. Of 22 ticks collected, 20 tested positive for Rickettsia. As Rh. sanguineus serves as a vector for both Rickettsia conorii and Ri. massiliae in southern France, all Rh. sanguineus isolates were tested by real-time PCR and conventional PCR to detect the 2 species. Nine ticks tested positive for Ri. conorii subsp. caspia (marking the first documentation of this subspecies in France), 7 tested positive for RI. massiliae, and 4 tested positive for both rickettsiae. This study is the first report of coinfection of Rh. sanguineus ticks with Ri. conorii and Ri. massiliae in southern France. (C) 2012 Elsevier GmbH. All rights reserved.

引用

页码：388 / 391

页数：4

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