Molecular Epidemiological Surveillance of Multidrug-Resistant Pseudomonas aeruginosa Isolates in a Pediatric Population of Patients with Cystic Fibrosis and Determination of Risk Factors for Infection with the Houston-1 Strain

被引：24

作者：

Luna, Ruth Ann ^{[1
,2
]}

Millecker, Laura A. ^{[2
]}

Webb, C. Renee ^{[2
]}

Mason, Sally K. ^{[3
,4
]}

Whaley, Elaine M. ^{[5
]}

Starke, Jeffrey R. ^{[3
,5
]}

Hiatt, Peter W. ^{[3
,4
]}

Versalovic, James ^{[1
,2
]}

机构：

[1] Baylor Coll Med, Dept Pathol & Immunol, Houston, TX 77030 USA

[2] Texas Childrens Hosp, Dept Pathol, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA

[4] Texas Childrens Hosp, Dept Pulm Med, Houston, TX 77030 USA

[5] Texas Childrens Hosp, Dept Infect Control & Prevent, Houston, TX 77030 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2013年 / 51卷 / 04期

关键词：

ADULT; PCR;

D O I：

10.1128/JCM.02157-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Multiyear molecular epidemiological surveillance of multidrug-resistant Pseudomonas aeruginosa (MRPA) in a pediatric cystic fibrosis care center identified an endemic MRPA strain (Houston-1). Recent hospitalization was found to be a statistically significant risk factor for acquisition of the endemic strain. Multiple infection control improvements led to the reduced incidence of the Houston-1 strain in the CF population.

引用

页码：1237 / 1240

页数：4

共 20 条

[11] Multiple combination bactericidal antibiotic testing for patients with cystic fibrosis infected with multiresistant strains of Pseudomonas aeruginosa [J].

Lang, BJ ;

Aaron, SD ;

Ferris, W ;

Hebert, PC ;

MacDonald, NE .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 162 (06) :2241-2245

[12] Outcomes of adults with cystic fibrosis infected with antibiotic-resistant Pseudomonas aeruginosa [J].

Lechtzin, N ;

John, M ;

Irizarry, R ;

Merlo, C ;

Diette, GB ;

Boyle, MP .

RESPIRATION, 2006, 73 (01) :27-33

[13] Genetic relatedness of Pseudomonas aeruginosa isolates among a paediatric cystic fibrosis patient cohort in Ireland [J].

Logan, Catriona ;

Habington, Adele ;

Lennon, Grainne ;

Grogan, Juanita ;

Byrne, Margaret ;

O'Leary, John ;

O'Sullivan, Niamh .

JOURNAL OF MEDICAL MICROBIOLOGY, 2012, 61 (01) :64-70

[14] Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growth [J].

Manos, Jim ;

Arthur, Jonathan ;

Rose, Barbara ;

Bell, Scott ;

Tingpej, Pholawat ;

Hu, Honghua ;

Webb, Jeremy ;

Kjelleberg, Staffan ;

Gorrell, Mark Douglas ;

Bye, Peter ;

Harbour, Colin .

FEMS MICROBIOLOGY LETTERS, 2009, 292 (01) :107-114

[15] Clinical outcome after early Pseudomonas aeruginosa infection in cystic fibrosis [J].

Nixon, GM ;

Armstrong, DS ;

Carzino, R ;

Carlin, JB ;

Olinsky, A ;

Robertson, CF ;

Grimwood, K .

JOURNAL OF PEDIATRICS, 2001, 138 (05) :699-704

[16] Clonal strains of Pseudomonas aeruginosa in paediatric and adult cystic fibrosis units [J].

O'Carroll, MR ;

Syrmis, MW ;

Wainwright, CE ;

Greer, RM ;

Mitchell, P ;

Coulter, C ;

Sloots, TP ;

Nissen, MD ;

Bell, SC .

EUROPEAN RESPIRATORY JOURNAL, 2004, 24 (01) :101-106

[17] Infection control recommendations for patients with cystic fibrosis: Microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmission [J].

Saiman, L ;

Siegel, J .

AMERICAN JOURNAL OF INFECTION CONTROL, 2003, 31 (03) :S6-S62

[18] Identification and characterization of transmissible Pseudomonas aeruginosa strains in cystic fibrosis patients in England and Wales [J].

Scott, FW ;

Pitt, TL .

JOURNAL OF MEDICAL MICROBIOLOGY, 2004, 53 (07) :609-615

[19] Rapid genotyping of Pseudomonas aeruginosa isolates harboured by adult and paediatric patients with cystic fibrosis using repetitive-element-based PCR assays [J].

Syrmis, MW ;

O'Carroll, MR ;

Sloots, TP ;

Coulter, C ;

Wainwright, CE ;

Bell, SC ;

Nissen, MD .

JOURNAL OF MEDICAL MICROBIOLOGY, 2004, 53 (11) :1089-1096

[20] Phenotypic characterization of clonal and nonclonal Pseudomonas aeruginosa strains isolated from lungs of adults with cystic fibrosis [J].

Tingpej, Pholawat ;

Smith, Lucas ;

Rose, Barbara ;

Zhu, Hua ;

Conibear, Tim ;

Nassafi, Khaled A. ;

Manos, Jim ;

Elkins, Mark ;

Bye, Peter ;

Willcox, Mark ;

Bell, Scott ;

Wainwright, Claire ;

Harbour, Colin .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (06) :1697-1704

← 1 2 →