Cesium carbonate mediated synthesis of 3-(α-hydroxyaryl)indoles

被引：17

作者：

Elayaraja, Rasokkiyam ^{[2
]}

Karunakaran, R. Joel ^{[1
]}

机构：

[1] Madras Christian Coll, Dept Chem, Madras 600059, Tamil Nadu, India

[2] Orchid Chem & Pharmaceut Ltd, Ctr Res & Dev, Madras 600119, Tamil Nadu, India

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 51期

关键词：

Cs2CO3; Indole; Aldehydes; 3-(alpha-Hydroxyaryl)indoles; ALKYLATION; ALDEHYDES; INDOLE; CONDENSATION;

D O I：

10.1016/j.tetlet.2012.10.002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 3-(alpha-hydroxyaryl)indoles have been synthesized by the reaction of aromatic aldehydes with indoles, catalyzed by cesium carbonate in DMF medium. The reactivity of the various alkali metal carbonates is discussed. The stability of 3-(alpha-hydroxyaryl)indoles is also discussed. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：6901 / 6904

页数：4

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