Synthesis, Crystal Structure and Biological Activity of A Novel 1,2,3-Thidiazole Compound

被引：0
作者：
Ke, Wei [1 ]
Sun, Na-Bo [1 ]
Wu, Hong-Ke [2 ]
机构：
[1] Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou 310015, Zhejiang, Peoples R China
[2] Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China
来源：
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN | 2013年 / 35卷 / 04期
关键词：
1,2,3-thiadiazole; synthesis; herbicidal activity; crystal structure; FUNGICIDAL ACTIVITY; 1,2,4-TRIAZOLE DERIVATIVES; DFT CALCULATION; 1,2,3-THIADIAZOLE; BIOACTIVITY;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new 1,2,3-thiadiazole compound was synthesized and characterized by H-1 NMR, MS and HRMS. The crystal structure of the title compound (C12H11ClN2O4S2, Mr = 346.80) has been determined by single-crystal X-ray diffraction. The crystal is of triclinic, space group P-1 with a = 8.4425(17) angstrom, b = 8.9801(18) angstrom, c = 9.859(2) angstrom, alpha = 84.36(3) degrees, beta = 86.71(3)degrees, gamma = 83.25(3)degrees, V = 737.9(3)angstrom(3), Z - 2, F(000) = 356, Dc = 1.561 g/cm(3), mu = 0.557 mm(-1), the final R1 - 0.0380 and wR2 = 0.0982 for 2160 observed reflections with I > 2 sigma(I). A total of 12585 reflections were collected, of which 2601 were independent (Rint = 0.0364). The herbicidal activity of title compound was determined, the results showed the title compound displayed excellent herbicidal activity against Brassica campestris.
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页码：1233 / 1238
页数：6
相关论文
共 27 条
  • [1] Chen PQ, 2012, ASIAN J CHEM, V24, P2808
  • [2] Synthesis and antiviral activity of new acrylamide derivatives containing 1,2,3-thiadiazole as inhibitors of hepatitis B virus replication
    Dong, Wei-Li
    Liu, Zheng-Xiao
    Liu, Xing-Hai
    Li, Zheng-Ming
    Zhao, Wei-Guang
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (05) : 1919 - 1926
  • [3] RAPID DIAGNOSIS OF ALS AHAS-RESISTANT WEEDS
    GERWICK, BC
    MIRELES, LC
    EILERS, RJ
    [J]. WEED TECHNOLOGY, 1993, 7 (02) : 519 - 524
  • [4] 1-Cyano-N-(2,4,5-trichlorophenyl)cyclopropane-1-carboxamide
    Liu, Hui-Jun
    Weng, Jian-Quan
    Tan, Cheng-Xia
    Liu, Xing-Hai
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1940 - U2137
  • [5] Liu X. F., 2011, ACTA CRYSTALLOGRAP E, V67
  • [6] Synthesis, Crystal Structure, and Fungicidal Activity of 5-(4-cyclopropyl-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)-4-methyl-1,2,3-thiadiazole
    Liu, Xing-Hai
    Weng, Jian-Quan
    Tan, Cheng-Xia
    [J]. JOURNAL OF CHEMISTRY, 2013, 2013
  • [7] Synthesis, bioactivity and DFT structure-activity relationship study of novel 1,2,3-thiadiazole derivatives
    Liu, Xing-Hai
    Zhao, Wei-Guang
    Wang, Bao-Lei
    Li, Zheng-Ming
    [J]. RESEARCH ON CHEMICAL INTERMEDIATES, 2012, 38 (08) : 1999 - 2008
  • [8] Synthesis, structure, and biological activity of novel (oxdi/tri)azoles derivatives containing 1,2,3-thiadiazole or methyl moiety
    Liu, Xing-Hai
    Pan, Li
    Weng, Jian-Quan
    Tan, Cheng-Xia
    Li, Yong-Hong
    Wang, Bao-Lei
    Li, Zheng-Ming
    [J]. MOLECULAR DIVERSITY, 2012, 16 (02) : 251 - 260
  • [9] (E)-(4-Bromobenzylidene)amino cyclopropanecarboxylate
    Liu, Xing-Hai
    Tan, Cheng-Xia
    Weng, Jian-Quan
    Liu, Hui-Jun
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2012, 68 : O493 - U1440
  • [10] Synthesis, crystal structure, bioactivity and DFT calculation of new oxime ester derivatives containing cyclopropane moiety
    Liu, Xing-Hai
    Pan, Li
    Tan, Cheng-Xia
    Weng, Jian-Quan
    Wang, Bao-Lei
    Li, Zheng-Ming
    [J]. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2011, 101 (03) : 143 - 147
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