Current Update on Biomarkers for Detection of Cancer: Comprehensive Analysis

被引：9
作者：
Kaushal, Ankur [1 ]
Kaur, Narinder [2 ]
Sharma, Surbhi [1 ]
Sharma, Anil K. K. [1 ]
Kala, Deepak [3 ]
Prakash, Hridayesh [4 ]
Gupta, Shagun [1 ]
机构：
[1] Maharishi Markandeshwar Deemed Univ, Dept Biotechnol, Ambala 134003, India
[2] Maharishi Markandeshwar Deemed Univ, Dept Microbiol, Ambala 134003, India
[3] Polish Acad Sci, Inst High Pressure Phys, NL Centera Tetrahertz Lab 11, 29-37 Sokolowska St, Warsaw, Poland
[4] Amity Univ Uttar Pradesh, Amity Ctr Translat Res, Noida 201313, India
来源：
VACCINES | 2022年 / 10卷 / 12期
关键词：
cancer biomarkers; electrochemical biosensors; nanomaterials; cancer; cancer screening; transducers; point of care systems; biosensing platforms; ELECTROCHEMICAL DNA BIOSENSOR; GOLD NANOPARTICLES; GRAPHENE OXIDE; LUNG-CANCER; PROSTATE-CANCER; ULTRASENSITIVE DETECTION; EXTRACELLULAR VESICLES; SANDWICH IMMUNOSENSOR; SENSITIVE DETECTION; PLATFORM;
D O I：
10.3390/vaccines10122138
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Early and effective diagnosis of cancer is decisive for its proper management. In this context biomarker-based cancer diagnosis is budding as one of the promising ways for early detection, disease progression monitoring, and effective cancer therapy. Integration of Biosensing devices with different metallic/nonmetallic nanoparticles offers amplification and multiplexing capabilities for simultaneous detection of cancer biomarkers (CB's). This study provides a comprehensive analysis of the most recent designs and fabrication methodologies designed for developing electrochemical biosensors (EB) for early detection of cancers. The role of biomarkers in cancer therapeutics is also discussed.
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页数：16
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共 102 条
  • [1] DNA-Based Nanobiosensors as an Emerging Platform for Detection of Disease
    Abu-Salah, Khalid M.
    Zourob, Mohammed M.
    Mouffouk, Fouzi
    Alrokayan, Salman A.
    Alaamery, Manal A.
    Ansari, Anees A.
    [J]. SENSORS, 2015, 15 (06) : 14539 - 14568
  • [2] Highly sensitive electrochemiluminescence detection of p53 protein using functionalized Ru-silica nanoporous@gold nanocomposite
    Afsharan, Hadi
    Navaeipour, Farzaneh
    Khalilzadeh, Balal
    Tajalli, Habib
    Mollabashi, Mahmood
    Ahar, Mohammad Johari
    Rashidi, Mohammad-Reza
    [J]. BIOSENSORS & BIOELECTRONICS, 2016, 80 : 146 - 153
  • [3] An electrochemical signal-on apta-cyto-sensor for quantitation of circulating human MDA-MB-231 breast cancer cells by transduction of electro-deposited non-spherical nanoparticles of gold
    Akhtartavan, S.
    Karimi, M.
    Sattarahmady, N.
    Heli, H.
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 178
  • [4] Gold nanoparticle modified capacitive sensor platform for multiple marker detection
    Altintas, Zeynep
    Kallempudi, Sreenivasa Saravan
    Gurbuz, Yasar
    [J]. TALANTA, 2014, 118 : 270 - 276
  • [5] An ultrasensitive electrochemical aptasensor for the determination of tumor exosomes based on click chemistry
    An, Yu
    Jin, Tongyu
    Zhu, Yuyuan
    Zhang, Fan
    He, Pingang
    [J]. BIOSENSORS & BIOELECTRONICS, 2019, 142
  • [6] Selective and ultrasensitive electrochemical immunosensing of NSE cancer biomarker in human serum using epoxy-substituted poly(pyrrole) polymer modified disposable ITO electrode
    Aydin, Elif Burcu
    Aydin, Muhammet
    Sezginturk, Mustafa Kemal
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2020, 306
  • [7] A sensitive and disposable electrochemical immunosensor for detection of SOX2, a biomarker of cancer
    Aydin, Elif Burcu
    Sezginturk, Mustafa Kemal
    [J]. TALANTA, 2017, 172 : 162 - 170
  • [8] Highly sensitive covalently functionalised integrated silicon nanowire biosensor devices for detection of cancer risk biomarker
    Azmi, M. A. Mohd
    Tehrani, Z.
    Lewis, R. P.
    Walker, K. -A. D.
    Jones, D. R.
    Daniels, D. R.
    Doak, S. H.
    Guy, O. J.
    [J]. BIOSENSORS & BIOELECTRONICS, 2014, 52 : 216 - 224
  • [9] An amplification-free electrochemical detection of exosomal miRNA-21 in serum samples
    Boriachek, Kseniia
    Umer, Muhammad
    Islam, Md Nazmul
    Gopalan, Vinod
    Lam, Alfred K.
    Nam-Trung Nguyen
    Shiddiky, Muhammad J. A.
    [J]. ANALYST, 2018, 143 (07) : 1662 - 1669
  • [10] Integrated bio-affinity nano-platform into a microfluidic immunosensor based on monoclonal bispecific trifunctional antibodies for the electrochemical determination of epithelial cancer biomarker
    Bravo, Karina
    Ortega, Francisco G.
    Messina, German A.
    Sanz, Maria I.
    Fernandez-Baldo, Martin A.
    Raba, Julio
    [J]. CLINICA CHIMICA ACTA, 2017, 464 : 64 - 71
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