Sensitive electrochemiluminescence sensor based on ordered mesoporous carbon composite film for dopamine

This work reports a sensitive electrochemiluminescence (ECL) detection strategy based on Ru(bpy)(3)(2+)/ordered mesoporous carbon/Nafion composite films modified glassy carbon electrode (GCE). Electrochemical and ECL behaviors of the prepared ECL sensors were studied with tri-n-propylamine (TPA) as coreactant. The proposed ECL sensor showed good reproducibility and high sensitivity to TPA with a wide linear range (4.75 x 10(-9) to 6.25 x 10(-4) M) and low detection limit (1.58 x 10(-9) M). Under the optimized conditions, the ECL sensor with TPA as coreactant was employed to detect a neurotransmitter dopamine (DA), for estimating its practical application in the medicine analysis. The present sensor displayed a good response to the concentration of DA from 5.0 x 10(-9) M to 5.0 x 10(-4) M. Moreover, the ECL sensor could be successfully applied to detect DA in real samples. The proposed signal amplification strategy for the preparation of ECL sensor could be easily attained and hold great promise for ultrasensitive medicine analysis. (C) 2014 Elsevier B.V. All rights reserved.