Incidence, timing and site of infections among pancreas transplant recipients

被引:26
作者
Bassetti, M
Salvalaggio, PRO
Topal, J
Lorber, MI
Friedman, AL
Andriole, VT
Basadonna, GP
机构
[1] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06510 USA
[2] Yale New Haven Med Ctr, New Haven, CT 06510 USA
[3] Yale Univ, Sch Med, Dept Surg, New Haven, CT 06510 USA
关键词
pancreas transplantation; bacterial; infections;
D O I
10.1016/j.jhin.2003.11.001
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The incidence, timing and site of infections among the different categories of pancreas transplant recipients were investigated. Patients were divided into three groups: pancreas transplant alone (PTA), pancreas after kidney transplant (PAK), or simultaneous pancreas and kidney (SPK) transplants. Length of follow-up, time to death, pancreas graft survival, incidence, timing and site of bacterial. infections were noted. Our study showed that at least 75% of pancreas transplant recipients experienced at least one infection (range from 77.8% in the PTA group to 86.7% in the PAK group). The SPK group presented the highest rate of infections with 35.1 infections per 1000/patient-days. Symptomatic urinary tract infections were the most common cause of infection in all patients. The incidence of infections was higher during the first month after transplantation, except for the SPK transplant group, where infections occurred over a longer time period. (C) 2003 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:184 / 190
页数:7
相关论文
共 28 条
[1]  
Baldi A, 1995, TRANSPLANT P, V27, P3116
[2]  
BARKER RJ, 1991, CLIN TRANSPLANT, V5, P403
[3]  
Benedetti E, 1996, ARCH SURG-CHICAGO, V131, P1054
[4]   Infections in renal transplant recipients receiving mycophenolate versus azathioprine-based immunosuppression [J].
Bernabeu-Wittel, M ;
Naranjo, M ;
Cisneros, JM ;
Cañas, E ;
Gentil, MA ;
Algarra, G ;
Pereira, P ;
González-Roncero, FJ ;
de Alarcón, A ;
Pachón, J .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2002, 21 (03) :173-180
[5]  
BRAYMAN KL, 1992, ARCH SURG-CHICAGO, V127, P38
[6]  
EVERETT JE, 1994, ARCH SURG-CHICAGO, V129, P1310
[7]   Simultaneous cadaver pancreas living-donor kidney transplantation: A new approach for the type 1 diabetic uremic patient [J].
Farney, AC ;
Cho, E ;
Schweitzer, EJ ;
Dunkin, B ;
Philosophe, B ;
Colonna, J ;
Jacobs, S ;
Jarrell, B ;
Flowers, JL ;
Bartlett, ST .
ANNALS OF SURGERY, 2000, 232 (05) :696-703
[8]   CDC DEFINITIONS FOR NOSOCOMIAL INFECTIONS, 1988 [J].
GARNER, JS ;
JARVIS, WR ;
EMORI, TG ;
HORAN, TC ;
HUGHES, JM .
AMERICAN JOURNAL OF INFECTION CONTROL, 1988, 16 (03) :128-140
[9]   Report for the International Pancreas Transplant Registry - 2000 [J].
Gruessner, AC ;
Sutherland, DER .
TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) :1643-1646
[10]   The surgical risk of pancreas transplantation in the cyclosporine era: An overview [J].
Gruessner, RWG ;
Sutherland, DER ;
Troppmann, C ;
Benedetti, E ;
Hakim, N ;
Dunn, DL ;
Gruessner, AC .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 1997, 185 (02) :128-144