Fiber and Functional Gastrointestinal Disorders

被引:302
作者
Eswaran, Shanti [1 ]
Muir, Jane [2 ]
Chey, William D. [1 ]
机构
[1] Univ Michigan Hlth Syst, Div Gastroenterol, Ann Arbor, MI 48109 USA
[2] Monash Univ, Melbourne, Vic 3004, Australia
关键词
IRRITABLE-BOWEL-SYNDROME; RANDOMIZED CLINICAL-TRIAL; CHRONIC IDIOPATHIC CONSTIPATION; HYDROLYZED GUAR GUM; DIETARY FIBER; COLONIC FERMENTATION; WHEAT BRAN; PRIMARY-CARE; CALCIUM POLYCARBOPHIL; ABDOMINAL SYMPTOMS;
D O I
10.1038/ajg.2013.63
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Despite years of advising patients to alter their dietary and supplementary fiber intake, the evidence surrounding the use of fiber for functional bowel disease is limited. This paper outlines the organization of fiber types and highlights the importance of assessing the fermentation characteristics of each fiber type when choosing a suitable strategy for patients. Fiber undergoes partial or total fermentation in the distal small bowel and colon leading to the production of short-chain fatty acids and gas, thereby affecting gastrointestinal function and sensation. When fiber is recommended for functional bowel disease, use of a soluble supplement such as ispaghula/psyllium is best supported by the available evidence. Even when used judiciously, fiber can exacerbate abdominal distension, flatulence, constipation, and diarrhea.
引用
收藏
页码:718 / 727
页数:10
相关论文
共 129 条
  • [61] Roughage revisited - The effect on intestinal function of inert plastic particles of different sizes and shape
    Lewis, SJ
    Heaton, KW
    [J]. DIGESTIVE DISEASES AND SCIENCES, 1999, 44 (04) : 744 - 748
  • [62] IS BRAN EFFICACIOUS IN IRRITABLE-BOWEL-SYNDROME - A DOUBLE-BLIND PLACEBO CONTROLLED CROSSOVER STUDY
    LUCEY, MR
    CLARK, ML
    LOWNDES, J
    DAWSON, AM
    [J]. GUT, 1987, 28 (02) : 221 - 225
  • [63] MANNING AP, 1977, LANCET, V2, P417
  • [64] The active fraction of psyllium seed husk
    Marlett, JA
    Fischer, MH
    [J]. PROCEEDINGS OF THE NUTRITION SOCIETY, 2003, 62 (01) : 207 - 209
  • [65] DIGESTIBILITY AND BULKING EFFECT OF ISPAGHULA HUSKS IN HEALTHY HUMANS
    MARTEAU, P
    FLOURIE, B
    CHERBUT, C
    CORREZE, JL
    PELLIER, P
    SEYLAZ, J
    RAMBAUD, JC
    [J]. GUT, 1994, 35 (12) : 1747 - 1752
  • [66] Effects of olestra and sorbitol consumption on objective measures of diarrhea: Impact of stool viscosity on common gastrointestinal symptoms
    McRorie, J
    Zorich, N
    Riccardi, K
    Bishop, L
    Filloon, T
    Wason, S
    Giannella, R
    [J]. REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2000, 31 (01) : 59 - 67
  • [67] Effects of fiber laxatives and calcium docusate on regional water content and viscosity of digests in the large intestine of the pig
    McRorie, J
    Pepple, S
    Rudolph, C
    [J]. DIGESTIVE DISEASES AND SCIENCES, 1998, 43 (04) : 738 - 745
  • [68] Characterization of propagating contractions in proximal colon of ambulatory mini pigs
    McRorie, J
    Greenwood-Van Meerveld, B
    Rudolph, C
    [J]. DIGESTIVE DISEASES AND SCIENCES, 1998, 43 (05) : 957 - 963
  • [69] McRorie JW, 1998, ALIMENT PHARM THERAP, V12, P491
  • [70] Pharmacological Basis for the Medicinal Use of Psyllium Husk (Ispaghula) in Constipation and Diarrhea
    Mehmood, Malik Hassan
    Aziz, Nauman
    Ghayur, Muhammad Nabeel
    Gilani, Anwarul-Hassan
    [J]. DIGESTIVE DISEASES AND SCIENCES, 2011, 56 (05) : 1460 - 1471