Impact of Multidrug-Resistant Organisms on Patients Considered for Lung Transplantation

被引:20
作者
Shoham, Shmuel [1 ]
Shah, Pali D. [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Transplant & Oncol Infect Dis Program, Baltimore, MD 21205 USA
关键词
Lung transplant; Multidrug-resistant organism; Microbiology; Epidemiology; SCEDOSPORIUM-APIOSPERMUM INFECTION; CYSTIC-FIBROSIS PATIENTS; RESPIRATORY-TRACT SPECIMENS; PSEUDOMONAS-AERUGINOSA; ACINETOBACTER-BAUMANNII; BURKHOLDERIA-CEPACIA; ASPERGILLUS-TERREUS; AIRWAY COLONIZATION; NONTUBERCULOUS MYCOBACTERIA; ANTIFUNGAL SUSCEPTIBILITY;
D O I
10.1016/j.idc.2013.02.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Infections with multidrug-resistant organisms are a growing problem in lung transplant recipients. Carriage of drug-resistant bacteria and fungi before transplantation is an important risk factor for such infections. In that regard Pseudomonas aeruginosa and species of Burkholderia, Acinetobacter, non-tuberculous mycobacteria and Scedosporium are particularly important. An understanding of the impact of these organisms is essential to the evaluation of lung transplant candidates. The microbiology, epidemiology, clinical manifestations, and approach to these pathogens before transplant are reviewed in this article.
引用
收藏
页码:343 / +
页数:17
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