Prediction and Identification of B-Cell Epitopes on Goose Parvovirus Capsid Protein

被引：0
作者：
Yu, Tian-fei [1 ,3 ]
Li, Ming [2 ]
Guo, Yuan [2 ]
Song, Guang-jun [2 ]
Li, Rong-xiu [3 ]
Xu, Ai-zhang [3 ]
Shao, Shu-li [1 ]
机构：
[1] Qiqihar Univ, Coll Life Sci & Agr Forestry, 42 Wenhua St, Qiqihar 161006, Peoples R China
[2] Qiqihar Univ, Coll Comp & Control Engn, Qiqihar 161006, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Life Sci Biotechnol, Key Lab, Minist Educ Microbial Metab, Shanghai 200240, Peoples R China
来源：
2011 INTERNATIONAL CONFERENCE ON ENVIRONMENT SCIENCE AND BIOTECHNOLOGY (ICESB 2011) | 2011年 / 8卷
关键词：
goose parvovirus; capsid protein; prediction; identification; epitope; LINKED-IMMUNOSORBENT-ASSAY; VIRAL DISEASE; VIRUS; GOSLINGS; GEESE;
D O I：
10.1016/j.proenv.2011.10.045
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The capsid protein (VP) gene of goose parvovirus (GPV) was translated into amino sequence by Editseq. The secondary structure and B-cell epitopes of the deduced protein were predicted by Protean. Combining the results according to these methods, the VP had complicated secondary structure. There were several potential B-cell epitopes on VP. By means of overlapping peptides expressed in Escherichia coli in combination with Western blot, B-cell epitopes were identified on VP. The results showed virtual linear immunodominant epitopes, which were found in seven fragments covering amino acid residues 35-81, 111-161, 423-453, 462-491, 531-577, 616-669, 678-732. (C) 2011 Published by Elsevier Ltd. Selection and/or peer-review under responsibility of the Asia-Pacific Chemical, Biological & Environmental Engineering Society (APCBEES)
引用
收藏
页码：284 / 288
页数：5
相关论文
共 50 条
[41]   Prediction of TGEV Spike Protein Secondary Structure and B Cell Epitopes [J].
Yu, Tian-lei ;
Shao, Shu-li ;
Xu, Xing-jun ;
Lv, Jian-wei ;
Li, Ming .
INFORMATION TECHNOLOGY AND AGRICULTURAL ENGINEERING, 2012, 134 :57-+
[42]   Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2 [J].
Farrera-Soler, Lluc ;
Daguer, Jean-Pierre ;
Barluenga, Sofia ;
Winssinger, Nicolas .
CHIMIA, 2021, 75 (04) :276-284
[43]   A machine-learning approach for predicting B-cell epitopes [J].
Rubinstein, Nimrod D. ;
Mayrose, Itay ;
Pupko, Tal .
MOLECULAR IMMUNOLOGY, 2009, 46 (05) :840-847
[44]   COBEpro: a novel system for predicting continuous B-cell epitopes [J].
Sweredoski, Michael J. ;
Baldi, Pierre .
PROTEIN ENGINEERING DESIGN & SELECTION, 2009, 22 (03) :113-120
[45]   Prediction of Pan-Specific B-Cell Epitopes From Nucleocapsid Protein of Hantaviruses Causing Hantavirus Cardiopulmonary Syndrome [J].
Kalaiselvan, Sagadevan ;
Sankar, Sathish ;
Ramamurthy, Mageshbabu ;
Ghosh, Asit Ranjan ;
Nandagopal, Balaji ;
Sridharan, Gopalan .
JOURNAL OF CELLULAR BIOCHEMISTRY, 2017, 118 (08) :2320-2324
[46]   Analysis of the Genome Sequence and Prediction of B-Cell Epitopes of the Envelope Protein of Middle East Respiratory Syndrome-Coronavirus [J].
Xie, Qian ;
He, Xiaoyan ;
Yang, Fangji ;
Liu, Xuling ;
Li, Ying ;
Liu, Yujing ;
Yang, ZhengMeng ;
Yu, Jianhai ;
Zhang, Bao ;
Zhao, Wei .
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 15 (04) :1344-1350
[47]   Identification of antigenic peptides derived from B-cell epitopes of nucleocapsid protein of mouse hepatitis virus for serological diagnosis [J].
Asano, Atsushi ;
Torigoe, Daisuke ;
Sasaki, Nobuya ;
Agui, Takashi .
JOURNAL OF VIROLOGICAL METHODS, 2011, 177 (01) :107-111
[48]   Prediction of Continuous B-cell Epitopes Using Long Short Term Memory Networks [J].
Cheng, Bin ;
Liu, Ling-yun ;
Qi, Zhao-hui ;
Yang, Hong-guang .
PROCEEDINGS OF 2018 6TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND COMPUTATIONAL BIOLOGY (ICBCB 2018), 2018, :55-59
[49]   B-cell epitopes: Discontinuity and conformational analysis [J].
Ferdous, Saba ;
Kelm, Sebastian ;
Baker, Terry S. ;
Shi, Jiye ;
Martin, Andrew C. R. .
MOLECULAR IMMUNOLOGY, 2019, 114 :643-650
[50]   Selection and combination of machine learning classifiers for prediction of linear B-cell epitopes on proteins [J].
Söllner, J .
JOURNAL OF MOLECULAR RECOGNITION, 2006, 19 (03) :209-214
12345