Synthesis of the core structure of the fungal metabolite benesudon: Use of oxidative decarboxylation

被引：6

作者：

Clive, DLJ ^{[1
]}

Minaruzzaman ^{[1
]}

Yang, HK ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 25期

关键词：

D O I：

10.1021/ol052131g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHIC] The core structure (5) of the fungal metabolite benesudon (1) was synthesized, the key step being oxidative decarboxylation of acid 17.

引用

页码：5581 / 5583

页数：3

共 6 条

[1] CYCLOGREGATIN, A NEW METABOLITE FROM ASPERGILLUS-PANAMENSIS [J].

ANKE, H ;

CASSER, I ;

SCHRAGE, M ;

STEGLICH, W .

JOURNAL OF ANTIBIOTICS, 1988, 41 (11) :1681-1684

[2] HETEROCYCLIZATION OF METHYL-6-HYDROXY-2-METHOXY-2-HEXENOATE AND METHYL-6-HYDROXY-2-METHOXY-2-HEPTENOATE [J].

FAIVRE, V ;

LILA, C ;

SAROLI, A ;

DOUTHEAU, A .

TETRAHEDRON, 1989, 45 (24) :7765-7782

[3]

HOFFMANN HMR, 1986, SYNTHESIS-STUTTGART, P548

[4] SCOPE AND MECHANISM OF DEPROTECTION OF CARBOXYLIC ESTERS BY BIS(TRIBUTYLTIN) OXIDE [J].

SALOMON, CJ ;

MATA, EG ;

MASCARETTI, OA .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (24) :7259-7266

[5] Benesudon, a new antibiotic fungal metabolite from cultures of Mollisia benesuada (Tul) Phill [J].

Thines, E ;

Arendholz, WR ;

Anke, H ;

Sterner, O .

JOURNAL OF ANTIBIOTICS, 1997, 50 (01) :13-17

[6] Ketene acetal and spiroacetal constituents of the marine fungus Aigialus parvus BCC 5311 [J].

Vongvilai, P ;

Isaka, M ;

Kittakoop, P ;

Srikitikulchai, P ;

Kongsaeree, P ;

Thebtaranonth, Y .

JOURNAL OF NATURAL PRODUCTS, 2004, 67 (03) :457-460

← 1 →