Curvature-driven membrane lipid and protein distribution
被引:44
|
作者:
Callan-Jones, Andrew
论文数: 0引用数: 0
h-index: 0
机构:
CNRS, Lab Charles Coulomb, UMR 5207, F-34095 Montpellier, France
Univ Montpellier 2, F-34095 Montpellier, FranceCNRS, Lab Charles Coulomb, UMR 5207, F-34095 Montpellier, France
Callan-Jones, Andrew
[1
,2
]
Bassereau, Patricia
论文数: 0引用数: 0
h-index: 0
机构:
Inst Curie, Ctr Rech, F-75248 Paris 05, France
CNRS, PhysicoChim Curie, UMR168, F-75248 Paris, France
Univ Paris 06, F-75252 Paris, FranceCNRS, Lab Charles Coulomb, UMR 5207, F-34095 Montpellier, France
Bassereau, Patricia
[3
,4
,5
]
机构:
[1] CNRS, Lab Charles Coulomb, UMR 5207, F-34095 Montpellier, France
[2] Univ Montpellier 2, F-34095 Montpellier, France
[3] Inst Curie, Ctr Rech, F-75248 Paris 05, France
[4] CNRS, PhysicoChim Curie, UMR168, F-75248 Paris, France
Membrane curvature;
Lipid sorting;
Protein sorting;
In vitro experiments;
Spontaneous curvature;
Bending rigidity;
N-BAR proteins;
Protein insertion;
Amphipathic helices;
Protein scaffold;
ENDOPHILIN N-BAR;
AMPHIPATHIC HELICES;
TUBULAR MEMBRANES;
STRUCTURAL BASIS;
DOMAINS;
MECHANISMS;
GENERATION;
BILAYERS;
RAFTS;
AMPHIPHYSIN;
D O I:
10.1016/j.cossms.2013.08.004
中图分类号:
T [工业技术];
学科分类号:
08 ;
摘要:
Cellular transport requires that membranes have the ability to recruit specific lipids and proteins to particular positions and at specific times. Here, we review recent work showing that lipids and proteins can be redistributed by spatially varying membrane curvature, without necessarily the need for biochemical targeting signals. We present here an emerging understanding of the various mechanisms by which membrane curvature can sort lipids and proteins, providing the experimental methods in addition to the supporting theoretical concepts. (C) 2013 Elsevier Ltd. All rights reserved.
机构:
Columbia Univ, Dept Chem Engn, New York, NY 10027 USA
Columbia Univ, Irving Med Ctr, Dept Genet & Dev, Columbia Stem Cell Initiat, New York, NY 10032 USASorbonne Univ, Univ PSL, Lab Physico Chim Curie, CNRS,UMR168,Inst Curie, F-75005 Paris, France
Simunovic, Mijo
Sorre, Benoit
论文数: 0引用数: 0
h-index: 0
机构:
Sorbonne Univ, Univ PSL, Lab Physico Chim Curie, CNRS,UMR168,Inst Curie, F-75005 Paris, France
Univ Paris, CNRS, UMR 7057, Lab Mat Syst Complexes, Paris, FranceSorbonne Univ, Univ PSL, Lab Physico Chim Curie, CNRS,UMR168,Inst Curie, F-75005 Paris, France
机构:
China Univ Petr East China, Coll Pipeline & Civil Engn, Qingdao 266580, Peoples R ChinaChina Univ Petr East China, Coll Pipeline & Civil Engn, Qingdao 266580, Peoples R China
Li, Shanpeng
Liu, Jianlin
论文数: 0引用数: 0
h-index: 0
机构:
China Univ Petr East China, Coll Pipeline & Civil Engn, Qingdao 266580, Peoples R ChinaChina Univ Petr East China, Coll Pipeline & Civil Engn, Qingdao 266580, Peoples R China
Liu, Jianlin
Hou, Jian
论文数: 0引用数: 0
h-index: 0
机构:
China Univ Petr East China, Coll Petr Engn, Qingdao 266580, Peoples R ChinaChina Univ Petr East China, Coll Pipeline & Civil Engn, Qingdao 266580, Peoples R China