Exacerbation of recalcitrant cutaneous sarcoidosis with adalimumab - a paradoxical effect? A case report

被引：13

作者：

Santos, Guida ^{[1
]}

Sousa, Lourdes Emerenciano ^{[1
]}

Bruno Lopes Joao, Alexandre Miguel ^{[1
]}

机构：

[1] Ctr Hosp Lisboa Cent, Santo Antonio dos Capuchos Hosp, Dept Dermatol & Venereol, Oporto, Portugal

来源：

ANAIS BRASILEIROS DE DERMATOLOGIA | 2013年 / 88卷 / 06期

关键词：

Biological agents; Biological treatment; Sarcoidosis; Tumor necrosis factor-alpha; ANTI-TNF;

D O I：

10.1590/abd1806-4841.20132487

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab.

引用

页码：26 / 28

页数：3

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