Delivery of anti-HIV bNAbs by viral vectors

被引：4

作者：

Caskey, Marina ^{[1
]}

机构：

[1] Rockefeller Univ, Lab Mol Immunol, New York, NY 10065 USA

来源：

LANCET HIV | 2019年 / 6卷 / 04期

关键词：

ANTIBODIES;

D O I：

10.1016/S2352-3018(19)30041-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：E207 / E208

页数：3

共 12 条

[1] Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals [J].

Bar-On, Yotam ;

Gruell, Henning ;

Schoofs, Till ;

Pai, Joy A. ;

Nogueira, Lilian ;

Butler, Allison L. ;

Millard, Katrina ;

Lehmann, Clara ;

Suarez, Isabelle ;

Oliveira, Thiago Y. ;

Karagounis, Theodora ;

Cohen, Yehuda Z. ;

Wyen, Christoph ;

Scholten, Stefan ;

Handl, Lisa ;

Belblidia, Shiraz ;

Dizon, Juan P. ;

Vehreschild, Joerg J. ;

Witmer-Pack, Maggi ;

Shimeliovich, Irina ;

Jain, Kanika ;

Fiddike, Kerstin ;

Seaton, Kelly E. ;

Yates, Nicole L. ;

Horowitz, Jill ;

Gulick, Roy M. ;

Pfeifer, Nico ;

Tomaras, Georgia D. ;

Seaman, Michael S. ;

Faetkenheuer, Gerd ;

Caskey, Marina ;

Klein, Florian ;

Nussenzweig, Michel C. .

NATURE MEDICINE, 2018, 24 (11) :1701-+

[2] Signaling by Antibodies: Recent Progress [J].

Bournazos, Stylianos ;

Wang, Taia T. ;

Dahan, Rony ;

Maamary, Jad ;

Ravetch, Jeffrey V. .

ANNUAL REVIEW OF IMMUNOLOGY, VOL 35, 2017, 35 :285-311

[3] Broadly neutralizing antibodies for treatment and prevention of HIV-1 infection [J].

Cohen, Yehuda Z. ;

Caskey, Marina .

CURRENT OPINION IN HIV AND AIDS, 2018, 13 (04) :366-373

[4] Progress toward active or passive HIV-1 vaccination [J].

Escolano, Amelia ;

Dosenovic, Pia ;

Nussenzweig, Michel C. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2017, 214 (01) :3-16

[5] Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies [J].

Fuchs, Sebastian P. ;

Desrosiers, Ronald C. .

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2016, 3 :16068

[6] AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity [J].

Fuchs, Sebastian P. ;

Martinez-Navio, Jose M. ;

Piatak, Michael, Jr. ;

Lifson, Jeffrey D. ;

Gao, Guangping ;

Desrosiers, Ronald C. .

PLOS PATHOGENS, 2015, 11 (08)

[7] Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys [J].

Johnson, Philip R. ;

Schnepp, Bruce C. ;

Zhang, Jianchao ;

Connell, Mary J. ;

Greene, Sean M. ;

Yuste, Eloisa ;

Desrosiers, Ronald C. ;

Clark, K. Reed .

NATURE MEDICINE, 2009, 15 (08) :901-U99

[8] Antibodies in HIV-1 Vaccine Development and Therapy [J].

Klein, Florian ;

Mouquet, Hugo ;

Dosenovic, Pia ;

Scheid, Johannes F. ;

Scharf, Louise ;

Nussenzweig, Michel C. .

SCIENCE, 2013, 341 (6151) :1199-1204

[9] Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1 [J].

Lin, Allen ;

Balazs, Alejandro B. .

RETROVIROLOGY, 2018, 15

[10] Combination therapy with anti-HIV-1 antibodies maintains viral suppression [J].

Mendoza, Pilar ;

Gruell, Henning ;

Nogueira, Lilian ;

Pai, Joy A. ;

Butler, Allison L. ;

Millard, Katrina ;

Lehmann, Clara ;

Suarez, Isabelle ;

Oliveira, Thiago Y. ;

Lorenzi, Julio C. C. ;

Cohen, Yehuda Z. ;

Wyen, Christoph ;

Kuemmerle, Tim ;

Karagounis, Theodora ;

Lu, Ching-Lan ;

Handl, Lisa ;

Unson-O'Brien, Cecilia ;

Patel, Roshni ;

Ruping, Carola ;

Schlotz, Maike ;

Witmer-Pack, Maggi ;

Shimeliovich, Irina ;

Kremer, Gisela ;

Thomas, Eleonore ;

Seaton, Kelly E. ;

Horowitz, Jill ;

West, Anthony P., Jr. ;

Bjorkman, Pamela J. ;

Tomaras, Georgia D. ;

Gulick, Roy M. ;

Pfeifer, Nico ;

Faetkenheuer, Gerd ;

Seaman, Michael S. ;

Klein, Florian ;

Caskey, Marina ;

Nussenzweig, Michel C. .

NATURE, 2018, 561 (7724) :479-+

← 1 2 →